Supplemental Choline Modulates Growth Performance and Gut Inflammation by Altering the Gut Microbiota and Lipid Metabolism in Weaned Piglets

Whether dietary choline and bile acids affect lipid use via gut microbiota is unclear. This study aimed to investigate the effect of choline and bile acids on growth performance, lipid use, intestinal immunology, gut microbiota, and bacterial metabolites in weaned piglets. A total of 128 weaned pigl...

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Veröffentlicht in:	The Journal of nutrition 2021-01, Vol.151 (1), p.20-29
Hauptverfasser:	Qiu, Yueqin, Liu, Shilong, Hou, Lei, Li, Kebiao, Wang, Li, Gao, Kaiguo, Yang, Xuefen, Jiang, Zongyong
Format:	Artikel
Sprache:	eng
Schlagworte:	Abundance Acids Animals bacterial metabolites Bile acids Bile Acids and Salts - administration & dosage Bile Acids and Salts - pharmacology Body weight Choline Choline - administration & dosage Cytokines - genetics Cytokines - metabolism Diet Dietary Supplements Digestive system Factorial design Female Gastrointestinal Microbiome - drug effects Gastrointestinal tract Gene expression Gene Expression Regulation - drug effects growth performance gut inflammation gut microbiota Immunology Inflammation - veterinary Interleukin 1 Interleukin 10 Intestinal Diseases - prevention & control Intestinal Diseases - veterinary Intestinal microflora Intestine Lactobacillus Lipase Lipid metabolism Lipid Metabolism - drug effects lipid use Lipids Male Metabolites Microbiota MyD88 protein NF-κB protein Parabacteroides Receptors, Cytoplasmic and Nuclear - metabolism Swine - growth & development Swine Diseases - prevention & control TLR4 protein Toll-like receptors Transcriptome Tumor necrosis factor-α weaned piglets
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