Next generation organofluorine containing blockbuster drugs

[Display omitted] •Selected organofluorine-containing blockbuster drugs were profiled.•General aspects of the biological properties of these compounds were briefly introduced.•The synthetic methods for preparation of these organofluorine-containing drugs were presented. The role of organo-fluorine c...

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Veröffentlicht in:	Journal of fluorine chemistry 2020-11, Vol.239, p.109639, Article 109639
Hauptverfasser:	Han, Jianlin, Remete, Attila Márió, Dobson, Luca S., Kiss, Lorand, Izawa, Kunisuke, Moriwaki, Hiroki, Soloshonok, Vadim A., O’Hagan, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Blockbuster drugs Diabetes mellitus Disease states Drug development Drugs Efavirenz Electronegativity Emtricitabine Fluorinated pharmaceuticals Fluorine Fluorine compounds Food industry Hepatitis Hepatitis C HIV Human immunodeficiency virus Immunomodulation Mental disorders Mode of action Organic chemistry Palmitic acid Prostate cancer Schizophrenia Synthetic routes
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