Catalytic Synthesis of N-Aryladamantane-1-carboxamides Using Phosphorus Trichloride

N -Aryl(benzyl)adamantane-1-carboxamides were synthesized in 54–87% yields by reaction of adamantane-1-carboxylic acid with aromatic amines in the presence of phosphorus trichloride, 4-dimethylaminopyridine, and triethylamine on heating at 80°C for 8 h.

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Veröffentlicht in:Russian journal of organic chemistry 2020-12, Vol.56 (12), p.2251-2253
Hauptverfasser: Shishkin, E. V., Vo, T. L. Q., Popov, Yu. V., Zotov, Yu. L., Nguyen, T. L., Shishkin, V. E., Sokolov, N. K.
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container_end_page 2253
container_issue 12
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container_title Russian journal of organic chemistry
container_volume 56
creator Shishkin, E. V.
Vo, T. L. Q.
Popov, Yu. V.
Zotov, Yu. L.
Nguyen, T. L.
Shishkin, V. E.
Sokolov, N. K.
description N -Aryl(benzyl)adamantane-1-carboxamides were synthesized in 54–87% yields by reaction of adamantane-1-carboxylic acid with aromatic amines in the presence of phosphorus trichloride, 4-dimethylaminopyridine, and triethylamine on heating at 80°C for 8 h.
doi_str_mv 10.1134/S1070428020120337
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subjects Amines
Aromatic compounds
Carboxylic acids
Chemical synthesis
Chemistry
Chemistry and Materials Science
Chlorides
Organic Chemistry
Phosphorus
Triethylamine
title Catalytic Synthesis of N-Aryladamantane-1-carboxamides Using Phosphorus Trichloride
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