Optimal control for a mathematical model for chemotherapy with pharmacometrics

An optimal control problem for an abstract mathematical model for cancer chemotherapy is considered. The dynamics is for a single drug and includes pharmacodynamic (PD) and pharmacokinetic (PK) models. The aim is to point out qualitative changes in the structures of optimal controls that occur as th...

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Veröffentlicht in:	Mathematical modelling of natural phenomena 2020, Vol.15, p.69
Hauptverfasser:	Leszczyński, Maciej, Ledzewicz, Urszula, Schättler, Heinz
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Antiangiogenics Chemotherapy Mathematical analysis Mathematical models Optimal control Pharmacodynamics Pharmacokinetics Pharmacology
Online-Zugang:	Volltext
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