Salmonella Infection in Nursery Piglets and Its Role in the Spread of Salmonellosis to Further Production Periods
Few studies have focused on assessing Salmonella infection in the nursery and its role in further pig production periods. Mesenteric lymph nodes, intestinal content, and meat juice from 389 6-week-old male piglets intended for human consumption from five breeding farms and 191 pooled floor fecal sam...
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| description | Few studies have focused on assessing Salmonella infection in the nursery and its role in further pig production periods. Mesenteric lymph nodes, intestinal content, and meat juice from 389 6-week-old male piglets intended for human consumption from five breeding farms and 191 pooled floor fecal samples from gilt development units (GDU) from the same farms were analyzed to estimate and characterize (by pulsed-field gel electrophoresis and antimicrobial resistance analyses) Salmonella infection. The prevalence of infection and shedding among piglets was 36.5% and 37.3%, respectively, shedding being significantly associated with infection (Odds Ratio = 12.7; CI 7.3-22.0). Salmonella Rissen; S. 4,[5],12:i:-; and S. Derby were the most common serotypes. A low level of Salmonella-specific maternal antibodies at the beginning of the nursery period suggested it was a period of high risk of infection. Resistance to 3rd- and 4th-generation cephalosporins was detected in piglet isolates although the piglets never received antibiotics, indicating they could be vectors of antimicrobial resistance. The same Salmonella clones were detected in piglet and GDU isolates, suggesting that infected piglets play a significant role in the infection of gilts and consequently of finishing pigs in the case of production farms. The control of Salmonella infection in nursery piglets may decrease the risk of abattoir and carcass contamination. |
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Mesenteric lymph nodes, intestinal content, and meat juice from 389 6-week-old male piglets intended for human consumption from five breeding farms and 191 pooled floor fecal samples from gilt development units (GDU) from the same farms were analyzed to estimate and characterize (by pulsed-field gel electrophoresis and antimicrobial resistance analyses) Salmonella infection. The prevalence of infection and shedding among piglets was 36.5% and 37.3%, respectively, shedding being significantly associated with infection (Odds Ratio = 12.7; CI 7.3-22.0). Salmonella Rissen; S. 4,[5],12:i:-; and S. Derby were the most common serotypes. A low level of Salmonella-specific maternal antibodies at the beginning of the nursery period suggested it was a period of high risk of infection. Resistance to 3rd- and 4th-generation cephalosporins was detected in piglet isolates although the piglets never received antibiotics, indicating they could be vectors of antimicrobial resistance. The same Salmonella clones were detected in piglet and GDU isolates, suggesting that infected piglets play a significant role in the infection of gilts and consequently of finishing pigs in the case of production farms. The control of Salmonella infection in nursery piglets may decrease the risk of abattoir and carcass contamination.</description><identifier>ISSN: 2076-0817</identifier><identifier>EISSN: 2076-0817</identifier><identifier>DOI: 10.3390/pathogens10020123</identifier><identifier>PMID: 33504097</identifier><language>eng</language><publisher>BASEL: Mdpi</publisher><subject>Abattoirs ; Age ; Antibiotics ; Antibodies ; Antimicrobial agents ; Antimicrobial resistance ; Bacterial infections ; Cephalosporins ; Drug resistance ; Electrophoresis ; Farms ; Feces ; Gel electrophoresis ; Health risks ; Hogs ; Infections ; Intestine ; Life Sciences & Biomedicine ; Low level ; Lymph nodes ; Meat ; Microbiology ; nursery piglets ; Pathogens ; PFGE ; prevalence ; Pulsed-field gel electrophoresis ; Salmonella ; Salmonellosis ; Science & Technology ; Serology ; Serotypes ; Shedding ; swine ; Swine production ; Weaning</subject><ispartof>Pathogens (Basel), 2021-01, Vol.10 (2), p.123, Article 123</ispartof><rights>2021. This work is licensed under http://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2021 by the authors. 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>true</woscitedreferencessubscribed><woscitedreferencescount>11</woscitedreferencescount><woscitedreferencesoriginalsourcerecordid>wos000622867500001</woscitedreferencesoriginalsourcerecordid><citedby>FETCH-LOGICAL-c493t-83023d70523896eedef6f661d8a1d24a0fdc3d33f4c6d876d1492dbe4823e4ce3</citedby><cites>FETCH-LOGICAL-c493t-83023d70523896eedef6f661d8a1d24a0fdc3d33f4c6d876d1492dbe4823e4ce3</cites><orcidid>0000-0002-3017-3012 ; 0000-0002-1974-9025 ; 0000-0001-5442-7702 ; 0000-0002-9340-0665</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911055/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7911055/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,729,782,786,866,887,2106,2118,27933,27934,39267,53800,53802</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33504097$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bernad-Roche, Maria</creatorcontrib><creatorcontrib>Casanova-Higes, Alejandro</creatorcontrib><creatorcontrib>Marin-Alcala, Clara M.</creatorcontrib><creatorcontrib>Cebollada-Solanas, Alberto</creatorcontrib><creatorcontrib>Mainar-Jaime, Raul C.</creatorcontrib><title>Salmonella Infection in Nursery Piglets and Its Role in the Spread of Salmonellosis to Further Production Periods</title><title>Pathogens (Basel)</title><addtitle>PATHOGENS</addtitle><addtitle>Pathogens</addtitle><description>Few studies have focused on assessing Salmonella infection in the nursery and its role in further pig production periods. Mesenteric lymph nodes, intestinal content, and meat juice from 389 6-week-old male piglets intended for human consumption from five breeding farms and 191 pooled floor fecal samples from gilt development units (GDU) from the same farms were analyzed to estimate and characterize (by pulsed-field gel electrophoresis and antimicrobial resistance analyses) Salmonella infection. The prevalence of infection and shedding among piglets was 36.5% and 37.3%, respectively, shedding being significantly associated with infection (Odds Ratio = 12.7; CI 7.3-22.0). Salmonella Rissen; S. 4,[5],12:i:-; and S. Derby were the most common serotypes. A low level of Salmonella-specific maternal antibodies at the beginning of the nursery period suggested it was a period of high risk of infection. Resistance to 3rd- and 4th-generation cephalosporins was detected in piglet isolates although the piglets never received antibiotics, indicating they could be vectors of antimicrobial resistance. 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Mesenteric lymph nodes, intestinal content, and meat juice from 389 6-week-old male piglets intended for human consumption from five breeding farms and 191 pooled floor fecal samples from gilt development units (GDU) from the same farms were analyzed to estimate and characterize (by pulsed-field gel electrophoresis and antimicrobial resistance analyses) Salmonella infection. The prevalence of infection and shedding among piglets was 36.5% and 37.3%, respectively, shedding being significantly associated with infection (Odds Ratio = 12.7; CI 7.3-22.0). Salmonella Rissen; S. 4,[5],12:i:-; and S. Derby were the most common serotypes. A low level of Salmonella-specific maternal antibodies at the beginning of the nursery period suggested it was a period of high risk of infection. Resistance to 3rd- and 4th-generation cephalosporins was detected in piglet isolates although the piglets never received antibiotics, indicating they could be vectors of antimicrobial resistance. The same Salmonella clones were detected in piglet and GDU isolates, suggesting that infected piglets play a significant role in the infection of gilts and consequently of finishing pigs in the case of production farms. The control of Salmonella infection in nursery piglets may decrease the risk of abattoir and carcass contamination.</abstract><cop>BASEL</cop><pub>Mdpi</pub><pmid>33504097</pmid><doi>10.3390/pathogens10020123</doi><tpages>14</tpages><orcidid>https://orcid.org/0000-0002-3017-3012</orcidid><orcidid>https://orcid.org/0000-0002-1974-9025</orcidid><orcidid>https://orcid.org/0000-0001-5442-7702</orcidid><orcidid>https://orcid.org/0000-0002-9340-0665</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Abattoirs Age Antibiotics Antibodies Antimicrobial agents Antimicrobial resistance Bacterial infections Cephalosporins Drug resistance Electrophoresis Farms Feces Gel electrophoresis Health risks Hogs Infections Intestine Life Sciences & Biomedicine Low level Lymph nodes Meat Microbiology nursery piglets Pathogens PFGE prevalence Pulsed-field gel electrophoresis Salmonella Salmonellosis Science & Technology Serology Serotypes Shedding swine Swine production Weaning |
| title | Salmonella Infection in Nursery Piglets and Its Role in the Spread of Salmonellosis to Further Production Periods |
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