Ultrasensitive Gastric Cancer Circulating Tumor Cellular CLDN18.2 RNA Detection Based on a Molecular Beacon

Gastric cancer (GC) is a major global cancer burden, and only HER2-targeted therapies have been approved in first line clinical therapy. CLDN18.2 has been regarded as a potential therapeutic target for gastrointestinal tumors, and global clinical trials have been in process. Hence, the precise, effi...

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Veröffentlicht in:	Analytical chemistry (Washington) 2021-01, Vol.93 (2), p.665-670
Hauptverfasser:	Fan, Linyang, Chong, Xiaoyi, Zhao, Minzhi, Jia, Fei, Wang, Zihua, Zhou, Ying, Lu, Xiao, Huang, Qiongrong, Li, Ping, Yang, Yanlian, Hu, Zhiyuan, Li, Qin, Zhang, Xiaotian, Shen, Lin
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acid sequence Analytical chemistry Antibodies Biomarkers, Tumor - blood Biopsy Cancer Cell Line, Tumor Chemistry Claudins - genetics Clinical trials ErbB-2 protein Gastric cancer Gene Expression Regulation, Neoplastic Humans Neoplastic Cells, Circulating Nucleotide sequence Phosphorothioate Ribonucleic acid RNA RNA - blood Selectivity Stomach Neoplasms - blood Stomach Neoplasms - diagnosis Therapeutic targets Tumors
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