Lavender and coriander essential oils and their main component linalool exert a protective effect against amyloid‐β neurotoxicity

Alzheimer's disease (AD) is a neurodegenerative disorder leading to cognitive deficits and cognitive decline. Since no cure or preventing therapy is currently available to counteract AD, natural‐derived compounds are investigated to find new potential neuroprotective agents for its treatment. I...

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Veröffentlicht in:	Phytotherapy research 2021-01, Vol.35 (1), p.486-493
Hauptverfasser:	Caputo, Lucia, Piccialli, Ilaria, Ciccone, Roselia, Caprariis, Paolo, Massa, Antonio, De Feo, Vincenzo, Pannaccione, Anna
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities Acyclic Monoterpenes - pharmacology Alzheimer Disease Alzheimer's disease Amyloid Amyloid beta-Peptides - toxicity amyloid‐β oligomers Animals Apoptosis Caspase Cell differentiation Chemical compounds Cognition Disorders - chemically induced Cognitive ability Cognitive Dysfunction Constituents coriander essential oil Coriandrum - chemistry Coriandrum sativum Essential oils In vivo methods and tests Lavandula Lavandula - chemistry lavender essential oil Linalool Neurodegeneration Neurodegenerative diseases Neuroprotection Neuroprotective agents Neuroprotective Agents - pharmacology Neurotoxicity Oils & fats Oils, Volatile - pharmacology Oligomers PC12 Cells Peptide Fragments - toxicity Pharmacology Pheochromocytoma cells Plant Oils - pharmacology Rats Reactive oxygen species Reactive Oxygen Species - metabolism
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