An Ultrasmall SnFe2O4 Nanozyme with Endogenous Oxygen Generation and Glutathione Depletion for Synergistic Cancer Therapy

The tumor microenvironment (TME) with the characteristics of severe hypoxia, overexpressed glutathione (GSH), and high levels of hydrogen peroxide (H2O2) dramatically limits the antitumor efficiency by monotherapy. Herein, a novel TME‐modulated nanozyme employing tin ferrite (SnFe2O4, abbreviated as...

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Veröffentlicht in:	Advanced functional materials 2021-01, Vol.31 (5), p.n/a
Hauptverfasser:	Feng, Lili, Liu, Bin, Xie, Rui, Wang, Dongdong, Qian, Cheng, Zhou, Weiqiang, Liu, Jiawei, Jana, Deblin, Yang, Piaoping, Zhao, Yanli
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Catalase chemodynamic therapy Computed tomography Depletion Free radicals Glutathione Hydrogen peroxide Hydroxyl radicals Hypoxia Magnetic properties Magnetic resonance imaging Materials science nanozyme Peroxidase Photodynamic therapy Photothermal conversion tin ferrite tumor microenvironment
Online-Zugang:	Volltext
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