Folate mediated targeted delivery of cinnamaldehyde loaded and FITC functionalized magnetic nanoparticles in breast cancer: in vitro , in vivo and pharmacokinetic studies

In the present study, cinnamaldehyde (CNAD) was loaded onto magnetic (Fe 3 O 4 ) nanoparticles (NPs) that were functionalized with FITC and folic acid (FiCF NPs) for imaging and active drug targeting in breast cancer cells. The particle size of the NPs was ∼10 nm while TGA analysis revealed 20% load...

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Veröffentlicht in:	New journal of chemistry 2021-01, Vol.45 (3), p.1500-1515
Hauptverfasser:	Shetty, Varsha, Jakhade, Alok, Shinde, Kavita, Chikate, Rajeev, Kaul-Ghanekar, Ruchika
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Biocompatibility Breast cancer Cinnamaldehyde Conjugation Cytoplasm Folic acid In vivo methods and tests Iron oxides Nanoparticles Pharmacokinetics Pharmacology Safety Toxicity
Online-Zugang:	Volltext
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