Maternal organic selenium supplementation during gestation improves the antioxidant capacity and reduces the inflammation level in the intestine of offspring through the NF-κB and ERK/Beclin-1 pathways

Selenium (Se) is postulated to protect against inflammation in the gut by attenuating oxidative stress. This study was conducted to investigate the effects of maternal 2-hydroxy-4-methylselenobutanoic acid (HMSeBA), an organic Se source, on the intestinal antioxidant capacity and inflammation level...

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Veröffentlicht in:	Food & function 2021-01, Vol.12 (1), p.315-327
Hauptverfasser:	Mou, Daolin, Ding, Dajiang, Yang, Min, Jiang, Xuemei, Zhao, Lianpeng, Che, Lianqiang, Fang, Zhengfeng, Xu, Shengyu, Lin, Yan, Zhuo, Yong, Li, Jian, Huang, Chao, Zou, Yuanfeng, Li, Lixia, Wu, De, Feng, Bin
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Diet Dietary supplements Extracellular signal-regulated kinase Gene expression Gestation IL-1β Inflammation Interleukin 6 Intestine Lipopolysaccharides NF-κB protein Offspring Oxidative stress Proteins Relative abundance Selenium Sodium selenite TOR protein Weaning
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