A Critical Review on the Synthesis of Natural Sodium Alginate Based Composite Materials: An Innovative Biological Polymer for Biomedical Delivery Applications
Sodium alginate (Na-Alg) is water-soluble, neutral, and linear polysaccharide. It is the derivative of alginic acid which comprises 1,4-β-d-mannuronic (M) and α-l-guluronic (G) acids and has the chemical formula (NaC6H7O6). It shows water-soluble, non-toxic, biocompatible, biodegradable, and non-imm...
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| creator | Ahmad, Awais Mubarak, N.M. Jannat, Fakiha Tul Ashfaq, Tayyaba Santulli, Carlo Rizwan, Muhammad Najda, Agnieszka Bin-Jumah, May Abdel-Daim, Mohamed M. Hussain, Shahid Ali, Shafaqat |
| description | Sodium alginate (Na-Alg) is water-soluble, neutral, and linear polysaccharide. It is the derivative of alginic acid which comprises 1,4-β-d-mannuronic (M) and α-l-guluronic (G) acids and has the chemical formula (NaC6H7O6). It shows water-soluble, non-toxic, biocompatible, biodegradable, and non-immunogenic properties. It had been used for various biomedical applications, among which the most promising are drug delivery, gene delivery, wound dressing, and wound healing. For different biomedical applications, it is used in different forms with the help of new techniques. That is the reason it had been blended with different polymers. In this review article, we present a comprehensive overview of the combinations of sodium alginate with natural and synthetic polymers and their biomedical applications involving delivery systems. All the scientific/technical issues have been addressed, and we have highlighted the recent advancements. |
| doi_str_mv | 10.3390/pr9010137 |
| format | Article |
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It is the derivative of alginic acid which comprises 1,4-β-d-mannuronic (M) and α-l-guluronic (G) acids and has the chemical formula (NaC6H7O6). It shows water-soluble, non-toxic, biocompatible, biodegradable, and non-immunogenic properties. It had been used for various biomedical applications, among which the most promising are drug delivery, gene delivery, wound dressing, and wound healing. For different biomedical applications, it is used in different forms with the help of new techniques. That is the reason it had been blended with different polymers. In this review article, we present a comprehensive overview of the combinations of sodium alginate with natural and synthetic polymers and their biomedical applications involving delivery systems. All the scientific/technical issues have been addressed, and we have highlighted the recent advancements.</description><identifier>ISSN: 2227-9717</identifier><identifier>EISSN: 2227-9717</identifier><identifier>DOI: 10.3390/pr9010137</identifier><language>eng</language><publisher>Basel: MDPI AG</publisher><subject>Alginic acid ; Atherosclerosis ; Biocompatibility ; Biodegradability ; Biomedical materials ; Cancer therapies ; Cell adhesion & migration ; Chemotherapy ; Composite materials ; Deoxyribonucleic acid ; DNA ; Drug delivery ; Drug delivery systems ; Food ; Gene transfer ; Hydrogels ; Immunogenicity ; Nanocomposites ; Pollutants ; Polymer blends ; Polymer matrix composites ; Polymers ; Polysaccharides ; Sodium ; Sodium alginate ; Tissue engineering ; Water chemistry ; Water treatment ; Wound healing</subject><ispartof>Processes, 2021-01, Vol.9 (1), p.137</ispartof><rights>2021. This work is licensed under http://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c292t-7fc332e932d4911cde1ca8015cb29e6aa44aa31e72d19300d12b84ff3af271b23</citedby><cites>FETCH-LOGICAL-c292t-7fc332e932d4911cde1ca8015cb29e6aa44aa31e72d19300d12b84ff3af271b23</cites><orcidid>0000-0002-1686-4271 ; 0000-0002-4341-2713 ; 0000-0002-3773-5196 ; 0000-0001-7083-2521 ; 0000-0002-1185-8884 ; 0000-0003-4774-3111 ; 0000-0002-3017-9924 ; 0000-0002-3513-2041 ; 0000-0003-4826-3339</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids></links><search><creatorcontrib>Ahmad, Awais</creatorcontrib><creatorcontrib>Mubarak, N.M.</creatorcontrib><creatorcontrib>Jannat, Fakiha Tul</creatorcontrib><creatorcontrib>Ashfaq, Tayyaba</creatorcontrib><creatorcontrib>Santulli, Carlo</creatorcontrib><creatorcontrib>Rizwan, Muhammad</creatorcontrib><creatorcontrib>Najda, Agnieszka</creatorcontrib><creatorcontrib>Bin-Jumah, May</creatorcontrib><creatorcontrib>Abdel-Daim, Mohamed M.</creatorcontrib><creatorcontrib>Hussain, Shahid</creatorcontrib><creatorcontrib>Ali, Shafaqat</creatorcontrib><title>A Critical Review on the Synthesis of Natural Sodium Alginate Based Composite Materials: An Innovative Biological Polymer for Biomedical Delivery Applications</title><title>Processes</title><description>Sodium alginate (Na-Alg) is water-soluble, neutral, and linear polysaccharide. It is the derivative of alginic acid which comprises 1,4-β-d-mannuronic (M) and α-l-guluronic (G) acids and has the chemical formula (NaC6H7O6). It shows water-soluble, non-toxic, biocompatible, biodegradable, and non-immunogenic properties. It had been used for various biomedical applications, among which the most promising are drug delivery, gene delivery, wound dressing, and wound healing. For different biomedical applications, it is used in different forms with the help of new techniques. That is the reason it had been blended with different polymers. In this review article, we present a comprehensive overview of the combinations of sodium alginate with natural and synthetic polymers and their biomedical applications involving delivery systems. 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Mubarak, N.M. ; Jannat, Fakiha Tul ; Ashfaq, Tayyaba ; Santulli, Carlo ; Rizwan, Muhammad ; Najda, Agnieszka ; Bin-Jumah, May ; Abdel-Daim, Mohamed M. ; Hussain, Shahid ; Ali, Shafaqat</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c292t-7fc332e932d4911cde1ca8015cb29e6aa44aa31e72d19300d12b84ff3af271b23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Alginic acid</topic><topic>Atherosclerosis</topic><topic>Biocompatibility</topic><topic>Biodegradability</topic><topic>Biomedical materials</topic><topic>Cancer therapies</topic><topic>Cell adhesion & migration</topic><topic>Chemotherapy</topic><topic>Composite materials</topic><topic>Deoxyribonucleic acid</topic><topic>DNA</topic><topic>Drug delivery</topic><topic>Drug delivery systems</topic><topic>Food</topic><topic>Gene transfer</topic><topic>Hydrogels</topic><topic>Immunogenicity</topic><topic>Nanocomposites</topic><topic>Pollutants</topic><topic>Polymer blends</topic><topic>Polymer matrix composites</topic><topic>Polymers</topic><topic>Polysaccharides</topic><topic>Sodium</topic><topic>Sodium alginate</topic><topic>Tissue engineering</topic><topic>Water chemistry</topic><topic>Water treatment</topic><topic>Wound healing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ahmad, Awais</creatorcontrib><creatorcontrib>Mubarak, N.M.</creatorcontrib><creatorcontrib>Jannat, Fakiha Tul</creatorcontrib><creatorcontrib>Ashfaq, Tayyaba</creatorcontrib><creatorcontrib>Santulli, Carlo</creatorcontrib><creatorcontrib>Rizwan, Muhammad</creatorcontrib><creatorcontrib>Najda, Agnieszka</creatorcontrib><creatorcontrib>Bin-Jumah, May</creatorcontrib><creatorcontrib>Abdel-Daim, Mohamed M.</creatorcontrib><creatorcontrib>Hussain, Shahid</creatorcontrib><creatorcontrib>Ali, Shafaqat</creatorcontrib><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>Materials Research Database</collection><collection>Materials Science Database</collection><collection>ProQuest Biological Science Collection</collection><collection>Biological Science Database</collection><collection>Materials Science Collection</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><jtitle>Processes</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ahmad, Awais</au><au>Mubarak, N.M.</au><au>Jannat, Fakiha Tul</au><au>Ashfaq, Tayyaba</au><au>Santulli, Carlo</au><au>Rizwan, Muhammad</au><au>Najda, Agnieszka</au><au>Bin-Jumah, May</au><au>Abdel-Daim, Mohamed M.</au><au>Hussain, Shahid</au><au>Ali, Shafaqat</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Critical Review on the Synthesis of Natural Sodium Alginate Based Composite Materials: An Innovative Biological Polymer for Biomedical Delivery Applications</atitle><jtitle>Processes</jtitle><date>2021-01-01</date><risdate>2021</risdate><volume>9</volume><issue>1</issue><spage>137</spage><pages>137-</pages><issn>2227-9717</issn><eissn>2227-9717</eissn><abstract>Sodium alginate (Na-Alg) is water-soluble, neutral, and linear polysaccharide. It is the derivative of alginic acid which comprises 1,4-β-d-mannuronic (M) and α-l-guluronic (G) acids and has the chemical formula (NaC6H7O6). It shows water-soluble, non-toxic, biocompatible, biodegradable, and non-immunogenic properties. It had been used for various biomedical applications, among which the most promising are drug delivery, gene delivery, wound dressing, and wound healing. For different biomedical applications, it is used in different forms with the help of new techniques. That is the reason it had been blended with different polymers. In this review article, we present a comprehensive overview of the combinations of sodium alginate with natural and synthetic polymers and their biomedical applications involving delivery systems. All the scientific/technical issues have been addressed, and we have highlighted the recent advancements.</abstract><cop>Basel</cop><pub>MDPI AG</pub><doi>10.3390/pr9010137</doi><orcidid>https://orcid.org/0000-0002-1686-4271</orcidid><orcidid>https://orcid.org/0000-0002-4341-2713</orcidid><orcidid>https://orcid.org/0000-0002-3773-5196</orcidid><orcidid>https://orcid.org/0000-0001-7083-2521</orcidid><orcidid>https://orcid.org/0000-0002-1185-8884</orcidid><orcidid>https://orcid.org/0000-0003-4774-3111</orcidid><orcidid>https://orcid.org/0000-0002-3017-9924</orcidid><orcidid>https://orcid.org/0000-0002-3513-2041</orcidid><orcidid>https://orcid.org/0000-0003-4826-3339</orcidid><oa>free_for_read</oa></addata></record> |
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| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; MDPI - Multidisciplinary Digital Publishing Institute |
| subjects | Alginic acid Atherosclerosis Biocompatibility Biodegradability Biomedical materials Cancer therapies Cell adhesion & migration Chemotherapy Composite materials Deoxyribonucleic acid DNA Drug delivery Drug delivery systems Food Gene transfer Hydrogels Immunogenicity Nanocomposites Pollutants Polymer blends Polymer matrix composites Polymers Polysaccharides Sodium Sodium alginate Tissue engineering Water chemistry Water treatment Wound healing |
| title | A Critical Review on the Synthesis of Natural Sodium Alginate Based Composite Materials: An Innovative Biological Polymer for Biomedical Delivery Applications |
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