Chemoimmunotherapy for the treatment of prostate cancer: Insights from mathematical modelling

•An eight-dimensional system describing the dynamics of prostate cancer (PCa) and chemoimmunotherapy is formulated.•Boundaries of a localizing domain containing all compact invariant sets of the PCa chemoimmunotherapy system are calculated.•Conditions are derived for the existence of a global attrac...

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Veröffentlicht in:	Applied Mathematical Modelling 2021-02, Vol.90, p.682-702
Hauptverfasser:	Valle, Paul A., Coria, Luis N., Carballo, Karla D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Asymptotic methods Asymptotic stability Chemotherapy Differential equations Immune system Immunotherapy In silico experimentations Liapunov direct method Mathematical analysis Mathematical models Metronomic chemotherapy Ordinary differential equations Prostate cancer Tumor elimination Upper bounds
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