Optimizing light delivery in scanning photoacoustic imaging for prostate

The purpose of this study was to optimize the light delivery method in a prostate photoacoustic imaging system. A three dimensional (3D) optical model of the human prostate was developed, and the optical energy distribution in the prostate was estimated via three-dimensional Monte Carlo simulation....

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Veröffentlicht in:Optoelectronics letters 2021, Vol.17 (1), p.53-58
Hauptverfasser: Peng, Dong-qing, Liu, Zhi-gao, Xu, Hui-zhen, Zhu, Li-li, Li, Hui
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Xu, Hui-zhen
Zhu, Li-li
Li, Hui
description The purpose of this study was to optimize the light delivery method in a prostate photoacoustic imaging system. A three dimensional (3D) optical model of the human prostate was developed, and the optical energy distribution in the prostate was estimated via three-dimensional Monte Carlo simulation. Then, the feasibility of prostate photoacoustic imaging (PAI) using two endoscopic light delivery methods was studied. Photoacoustic pressure generation and the corresponding photoacoustic images had been obtained and the comparisons were made between each other. Also, the results of cylinder diffusing light source with different lengths were compared. After that, phantom experiment was carried out to validate the simulation results. Our results would be significant in the optimizing photoacoustic imaging system for an accurate diagnosis of prostate cancer.
doi_str_mv 10.1007/s11801-021-0077-7
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subjects Energy distribution
Lasers
Light sources
Medical imaging
Monte Carlo simulation
Optical Devices
Optics
Optimization
Photonics
Physics
Physics and Astronomy
Prostate
Three dimensional models
title Optimizing light delivery in scanning photoacoustic imaging for prostate
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