Effect of pterois volitans (lionfish) venom on cholinergic and dopaminergic systems

[Display omitted] •Venom of P. volitans inhibits the growth of D. rerio embryos.•Venom of P. volitans affects dopaminergic neurons.•Venom of P. volitans mainly affects the α2 subunit of the nicotinic acetylcholine receptor.•Venom of P. volitans had an inhibitory effect on human neuronal α3β2 recepto...

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Veröffentlicht in:	Environmental toxicology and pharmacology 2020-07, Vol.77, p.103359-10, Article 103359
Hauptverfasser:	Becerra-Amezcua, Mayra P., Hernández-Sámano, Arisaí C., Puch-Hau, Carlos, Aguilar, Manuel B., Collí-Dulá, Reyna C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine Acetylcholine receptors Acetylcholine receptors (muscarinic) Acetylcholine receptors (nicotinic) Acetylcholinesterase Acetylcholinesterase - genetics Animals Cholinergic transmission Cholinergics Danio rerio Dopamine receptors Dopaminergic Dopaminergic Neurons - drug effects Embryo, Nonmammalian Embryogenesis Embryonic growth stage Embryos Fibrillation Fish Proteins - physiology Fish Venoms - toxicity Gene expression Growth hormones High performance liquid chromatography Humans Liquid chromatography mRNA nAChR α2 nAChR α3β2 Neurons Neurotransmission Oocytes - physiology Perciformes Pterois Receptors Receptors, Nicotinic - physiology Somites Venom Xenopus laevis Zebrafish
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