Targeting signalling pathways and the immune microenvironment of cancer stem cells — a clinical update

Cancer stem cells (CSCs) have important roles in tumour development, relapse and metastasis; the intrinsic self-renewal characteristics and tumorigenic properties of these cells provide them with unique capabilities to resist diverse forms of anticancer therapy, seed recurrent tumours, and dissemina...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature reviews. Clinical oncology 2020-04, Vol.17 (4), p.204-232
Hauptverfasser:	Clara, Joseph A., Monge, Cecilia, Yang, Yingzi, Takebe, Naoko
Format:	Artikel
Sprache:	eng
Schlagworte:	631/136/532/71 631/67/1059 692/308/575 692/699/67/1059/2325 692/700/565/1436/2185 Antineoplastic Agents - therapeutic use Cancer Cancer cells Cancer therapies Cell self-renewal Cellular proteins Cellular signal transduction Drug development Epithelial-Mesenchymal Transition - drug effects Epithelial-Mesenchymal Transition - immunology Genetic aspects Health aspects Homeostasis Humans Immune system Immune System - drug effects Immune System - immunology Immunotherapy Medicine Medicine & Public Health Metastases Methods Microenvironments Molecular Targeted Therapy - methods Neoplasm Recurrence, Local Neoplasms - drug therapy Neoplasms - immunology Neoplasms - pathology Neoplastic Stem Cells - drug effects Neoplastic Stem Cells - immunology Neoplastic Stem Cells - pathology Oncology Patient outcomes Phenotypes Progenitor cells Review Article Signal transduction Signal Transduction - drug effects Signal Transduction - immunology Stem cells Therapeutic applications Tumor Microenvironment - drug effects Tumor Microenvironment - immunology Tumors Wnt protein
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!