Richter transformation in chronic lymphocytic leukemia (CLL)—a pooled analysis of German CLL Study Group (GCLLSG) front line treatment trials

Richter transformation (RT) is defined as development of aggressive lymphoma in patients (pts) with CLL. The incidence rates of RT among pts with CLL range from 2 to 10%. The aim of this analysis is to report the frequency, characteristics and outcomes of pts with RT enrolled in trials of the GCLLSG...

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Veröffentlicht in:	Leukemia 2021-01, Vol.35 (1), p.169-176
Hauptverfasser:	Al-Sawaf, O., Robrecht, S., Bahlo, J., Fink, A. M., Cramer, P., v Tresckow, J., Lange, E., Kiehl, M., Dreyling, M., Ritgen, M., Dürig, J., Tausch, E., Schneider, C., Stilgenbauer, S., Wendtner, C. M., Fischer, K., Goede, Hallek, M., Eichhorst, B.
Format:	Artikel
Sprache:	eng
Schlagworte:	692/699/1541/1990/283/1895 692/699/67/1990/291/1621/1915 Adult Aged Aged, 80 and over Autografts B-cell lymphoma Biopsy Cancer Cancer Research Care and treatment Cell Transformation, Neoplastic - genetics Chronic lymphocytic leukemia Clinical trials Critical Care Medicine Development and progression Diagnosis Disease Progression Evaluation Female Genetic transformation Genetic Variation Germany Hematology Hodgkin's lymphoma Humans Intensive Internal Medicine Leukemia Leukemia, Lymphocytic, Chronic, B-Cell - genetics Leukemia, Lymphocytic, Chronic, B-Cell - pathology Leukemia, Lymphocytic, Chronic, B-Cell - therapy Lymphatic leukemia Lymphocytes B Lymphoma Lymphoma - etiology Lymphoma - mortality Lymphoma - pathology Lymphoma - therapy Male Medicine Medicine & Public Health Middle Aged Neoplasm Grading Neoplasm Staging Oncology Oncology, Experimental Prognosis Stem cell transplantation Stem cells Survival Analysis Time Factors Transplantation Young Adult
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