Transcriptional regulation by σ factor phosphorylation in bacteria

A major form of transcriptional regulation in bacteria occurs through the exchange of the primary σ factor of RNA polymerase (RNAP) with an alternative extracytoplasmic function (ECF) σ factor 1 . ECF σ factors are generally intrinsically active and are retained in an inactive state via the sequestr...

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Veröffentlicht in:	Nature microbiology 2020-03, Vol.5 (3), p.395-406
Hauptverfasser:	Iyer, Shankar Chandrashekar, Casas-Pastor, Delia, Kraus, David, Mann, Petra, Schirner, Kathrin, Glatter, Timo, Fritz, Georg, Ringgaard, Simon
Format:	Artikel
Sprache:	eng
Schlagworte:	631/326/41/1969 631/326/88 631/337/572 Bacteria Bacteria - genetics Bacteria - metabolism Biomedical and Life Sciences DNA, Bacterial - genetics DNA-directed RNA polymerase DNA-Directed RNA Polymerases Gene expression Gene Expression Regulation, Bacterial - drug effects Gene regulation Genes, Bacterial - genetics Infectious Diseases Kinases Letter Life Sciences Medical Microbiology Microbiology Models, Molecular Parasitology Phosphorylation Protein-Serine-Threonine Kinases - metabolism Proteomics RNA polymerase Sigma Factor - pharmacology Signal transduction Threonine Transcription Transcription, Genetic - drug effects Transcriptome Vibrio parahaemolyticus - genetics Vibrio parahaemolyticus - metabolism Virology
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