Suitability of transbronchial brushing cytology specimens for next‐generation sequencing in peripheral lung cancer

Next‐generation sequencing (NGS) enables the diagnosis of large numbers of gene aberrations during one examination, and precision medicine has been developed for patients with advanced non–small cell lung cancer (NSCLC). However, peripheral lung lesions account for the majority of advanced lung canc...

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Veröffentlicht in:	Cancer science 2021-01, Vol.112 (1), p.380-387
Hauptverfasser:	Furuya, Naoki, Matsumoto, Shingo, Kakinuma, Kazutaka, Morikawa, Kei, Inoue, Takeo, Saji, Hisashi, Goto, Koichi, Mineshita, Masamichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Adult Aged Aged, 80 and over Biopsy Biopsy, Needle - methods bronchial brushing Bronchoscopy Bronchoscopy - methods Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - pathology Cellular biology Clinical Research Cytology Deoxyribonucleic acid DNA DNA sequencing Female High-Throughput Nucleotide Sequencing Histology Humans Image-Guided Biopsy - methods Laboratories Life Sciences & Biomedicine Local anesthesia Lung cancer Lung Neoplasms - genetics Lung Neoplasms - pathology Lymphatic system Male Medicine Middle Aged Mutation Navigation systems next‐generation sequencing Non-small cell lung carcinoma nucleic acid yield Oncology Original Physiology Pleural effusion Precision medicine Ribonucleic acid RNA Science & Technology Small cell lung carcinoma Success success rate Tumor cells Ultrasonic imaging Ultrasonography, Interventional - methods
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