Gallic acid exerts anti-inflammatory, anti-oxidative stress, and nephroprotective effects against paraquat-induced renal injury in male rats

Paraquat (PRQ) is a toxic chemical compound that is very noxious to animals and humans. Gallic acid is a phenolic compound that has antioxidant properties. In this study, we evaluated the ameliorative effect of gallic acid against PRQ-induced renal injury and oxidative stress. In this research, the...

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Veröffentlicht in:	Naunyn-Schmiedeberg's archives of pharmacology 2021, Vol.394 (1), p.1-9
Hauptverfasser:	Nouri, Ali, Heibati, Fatemeh, Heidarian, Esfandiar
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine Transaminase - blood Animals Anti-Inflammatory Agents - pharmacology Anti-Inflammatory Agents - therapeutic use Antioxidants Antioxidants - pharmacology Antioxidants - therapeutic use Ascorbic acid Ascorbic Acid - metabolism Aspartate Aminotransferases - blood Biomedical and Life Sciences Biomedicine Carbonyl compounds Catalase Catalase - metabolism Creatinine Gallic acid Gallic Acid - pharmacology Gallic Acid - therapeutic use Gene expression Herbicides IL-1β Inflammation Interleukin-1beta - blood Interleukin-1beta - genetics Kidney - drug effects Kidney - metabolism Kidney - pathology Kidney Diseases - chemically induced Kidney Diseases - drug therapy Kidney Diseases - metabolism Kidney Diseases - pathology Kidneys Male Malondialdehyde - blood Neurosciences Original Article Oxidative stress Paraquat Pharmacology/Toxicology Protein Carbonylation - drug effects Pyruvic acid Rats Rats, Wistar Superoxide dismutase Superoxide Dismutase - metabolism Transaminase Urea Uric acid Uric Acid - blood
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