Fabrication, characterization, and in vivo biocompatibility evaluation of titanium-niobium implants
In this study, biocompatible titanium-niobium (Ti-Nb) alloys were fabricated by using powder metallurgy methods. Physical, morphological, thermal, and mechanical analyses were performed and their in vivo compatibility was evaluated. Besides α, β, and α″ martensitic phases, α+β Widmanstätten phase du...
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Veröffentlicht in: | Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine Journal of engineering in medicine, 2021-01, Vol.235 (1), p.99-108 |
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container_title | Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine |
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creator | Yolun, Abdurrahman Şimşek, Murat Kaya, Mehmet Annaç, Ebru Elibol Köm, Mustafa Çakmak, Ömer |
description | In this study, biocompatible titanium-niobium (Ti-Nb) alloys were fabricated by using powder metallurgy methods. Physical, morphological, thermal, and mechanical analyses were performed and their in vivo compatibility was evaluated. Besides α, β, and α″ martensitic phases, α+β Widmanstätten phase due to increasing sintering temperature was seen in the microstructure of the alloys. Phase transformation temperatures of the samples decreased as Nb content increased. The ratio of Nb in the samples affected their mechanical properties. No toxic effect was observed on implanted sites. This study shows that Ti-Nb alloys can be potentially used for orthopedic applications without any toxic effects. |
doi_str_mv | 10.1177/0954411920960854 |
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Physical, morphological, thermal, and mechanical analyses were performed and their in vivo compatibility was evaluated. Besides α, β, and α″ martensitic phases, α+β Widmanstätten phase due to increasing sintering temperature was seen in the microstructure of the alloys. Phase transformation temperatures of the samples decreased as Nb content increased. The ratio of Nb in the samples affected their mechanical properties. No toxic effect was observed on implanted sites. This study shows that Ti-Nb alloys can be potentially used for orthopedic applications without any toxic effects.</description><identifier>ISSN: 0954-4119</identifier><identifier>EISSN: 2041-3033</identifier><identifier>DOI: 10.1177/0954411920960854</identifier><identifier>PMID: 32988330</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Alloys ; Biocompatibility ; Fabrication ; In vivo methods and tests ; Mechanical properties ; Metallurgical analysis ; Metallurgy ; Niobium ; Orthopedics ; Phase transitions ; Powder metallurgy ; Sintering (powder metallurgy) ; Surgical implants ; Titanium ; Titanium base alloys ; Toxicity ; Transformation temperature</subject><ispartof>Proceedings of the Institution of Mechanical Engineers. 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Part H, Journal of engineering in medicine</title><addtitle>Proc Inst Mech Eng H</addtitle><description>In this study, biocompatible titanium-niobium (Ti-Nb) alloys were fabricated by using powder metallurgy methods. Physical, morphological, thermal, and mechanical analyses were performed and their in vivo compatibility was evaluated. Besides α, β, and α″ martensitic phases, α+β Widmanstätten phase due to increasing sintering temperature was seen in the microstructure of the alloys. Phase transformation temperatures of the samples decreased as Nb content increased. The ratio of Nb in the samples affected their mechanical properties. No toxic effect was observed on implanted sites. This study shows that Ti-Nb alloys can be potentially used for orthopedic applications without any toxic effects.</description><subject>Alloys</subject><subject>Biocompatibility</subject><subject>Fabrication</subject><subject>In vivo methods and tests</subject><subject>Mechanical properties</subject><subject>Metallurgical analysis</subject><subject>Metallurgy</subject><subject>Niobium</subject><subject>Orthopedics</subject><subject>Phase transitions</subject><subject>Powder metallurgy</subject><subject>Sintering (powder metallurgy)</subject><subject>Surgical implants</subject><subject>Titanium</subject><subject>Titanium base alloys</subject><subject>Toxicity</subject><subject>Transformation temperature</subject><issn>0954-4119</issn><issn>2041-3033</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp1kM1LAzEQxYMotlbvniTg1dXJ134cpVgVCl70vCTZrKbsbtYkW6h_vVtbFQTnMjDvN-_BQ-icwDUhWXYDheCckIJCkUIu-AGaUuAkYcDYIZpu5WSrT9BJCCsAIATSYzRhtMhzxmCK9EIqb7WM1nVXWL9JL3U03n7sL7KrsO3w2q4dVtZp1_ajomxj4wabtWyGLxC7GkcbZWeHNumsU-PGtu0b2cVwio5q2QRztt8z9LK4e54_JMun-8f57TLRLBUxybjSmgPllCowRo5TKK4rRQolmcpUrXnGBanr1FRU5WkqNFWVqEVBpck1m6HLnW_v3ftgQixXbvDdGFlSnrGMCp7zkYIdpb0LwZu67L1tpd-UBMptq-XfVseXi73xoFpT_Tx81zgCyQ4I8tX8pv5r-AmQsoF2</recordid><startdate>202101</startdate><enddate>202101</enddate><creator>Yolun, Abdurrahman</creator><creator>Şimşek, Murat</creator><creator>Kaya, Mehmet</creator><creator>Annaç, Ebru Elibol</creator><creator>Köm, Mustafa</creator><creator>Çakmak, Ömer</creator><general>SAGE Publications</general><general>SAGE PUBLICATIONS, INC</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QF</scope><scope>7QO</scope><scope>7QQ</scope><scope>7SC</scope><scope>7SE</scope><scope>7SP</scope><scope>7SR</scope><scope>7TA</scope><scope>7TB</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>F28</scope><scope>FR3</scope><scope>H8D</scope><scope>H8G</scope><scope>JG9</scope><scope>JQ2</scope><scope>K9.</scope><scope>KR7</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>P64</scope><orcidid>https://orcid.org/0000-0001-9710-2254</orcidid></search><sort><creationdate>202101</creationdate><title>Fabrication, characterization, and in vivo biocompatibility evaluation of titanium-niobium implants</title><author>Yolun, Abdurrahman ; 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Part H, Journal of engineering in medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yolun, Abdurrahman</au><au>Şimşek, Murat</au><au>Kaya, Mehmet</au><au>Annaç, Ebru Elibol</au><au>Köm, Mustafa</au><au>Çakmak, Ömer</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fabrication, characterization, and in vivo biocompatibility evaluation of titanium-niobium implants</atitle><jtitle>Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine</jtitle><addtitle>Proc Inst Mech Eng H</addtitle><date>2021-01</date><risdate>2021</risdate><volume>235</volume><issue>1</issue><spage>99</spage><epage>108</epage><pages>99-108</pages><issn>0954-4119</issn><eissn>2041-3033</eissn><abstract>In this study, biocompatible titanium-niobium (Ti-Nb) alloys were fabricated by using powder metallurgy methods. 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subjects | Alloys Biocompatibility Fabrication In vivo methods and tests Mechanical properties Metallurgical analysis Metallurgy Niobium Orthopedics Phase transitions Powder metallurgy Sintering (powder metallurgy) Surgical implants Titanium Titanium base alloys Toxicity Transformation temperature |
title | Fabrication, characterization, and in vivo biocompatibility evaluation of titanium-niobium implants |
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