Targeting receptor complexes: a new dimension in drug discovery

Targeting receptor proteins, such as ligand-gated ion channels and G protein-coupled receptors, has directly enabled the discovery of most drugs developed to modulate receptor signalling. However, as the search for novel and improved drugs continues, an innovative approach — targeting receptor compl...

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Veröffentlicht in:Nature reviews. Drug discovery 2020-12, Vol.19 (12), p.884-901
Hauptverfasser: Rosenbaum, Mette Ishøy, Clemmensen, Louise S., Bredt, David S., Bettler, Bernhard, Strømgaard, Kristian
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Sprache:eng
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