Development of gold(III) thiosemicarbazonate complex–loaded PLGA nanoparticles: characterization and sustained release studies

The gold(III) complex [AuCl(L 1 )] has been reported as a lead candidate for Chagas’ disease (CD) treatment. However, in order to be effective, the drug must first reach the target tissue and then be delivered in therapeutic amounts. In this context, nanoparticles (NPs) of poly(lactic-co-glycolic ac...

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Veröffentlicht in:	Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology 2020-11, Vol.22 (11), Article 339
Hauptverfasser:	Silva, Raphael T. C., Dalmolin, Luciana F., Moreto, Jéferson A., Oliveira, Carolina G., Machado, Antonio E. H., Lopez, Renata F. V., Maia, Pedro I. S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Characterization and Evaluation of Materials Chemistry and Materials Science Computer applications Controlled release Emulsification Evaporation Glycolic acid Gold Image resolution In vivo methods and tests Inorganic Chemistry Lasers Materials Science Nanoparticles Nanotechnology Optical Devices Optics Parasites Photonics Physical Chemistry Polydispersity Polylactide-co-glycolide Research Paper Stability analysis Sustained release Vector-borne diseases Zeta potential
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