Residue dissipation, evaluation of processing factor and safety assessment of hexythiazox and bifenazate residues during drying of grape to raisin

An analytical method for the simultaneous analysis of hexythiazox and bifenazate residues in grape and raisin was validated by liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis. The extraction method involved liquid-liquid extraction with ethyl acetate and dSPE cleanup with primary...

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Veröffentlicht in:Environmental science and pollution research international 2020-11, Vol.27 (33), p.41816-41823
Hauptverfasser: Thekkumpurath, Ahammed Shabeer, Girame, Rushali, Hingmire, Sandip, Jadhav, Manjusha, Jain, Prachi
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container_issue 33
container_start_page 41816
container_title Environmental science and pollution research international
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creator Thekkumpurath, Ahammed Shabeer
Girame, Rushali
Hingmire, Sandip
Jadhav, Manjusha
Jain, Prachi
description An analytical method for the simultaneous analysis of hexythiazox and bifenazate residues in grape and raisin was validated by liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis. The extraction method involved liquid-liquid extraction with ethyl acetate and dSPE cleanup with primary secondary amine (PSA). The drying of grape to raisin may increase or decrease residues of pesticides. During the raisin making process, the dissipation of residue was evaluated and the processing factor (PF) was established for drying. Dissipation data were best fitted to 1 st + 1 st -order kinetics with a half-life ranging between 6–10 days for hexythiazox and 5–6 days for bifenazate. The PF value for overall raisin making was found to be 0.20–0.36 for hexythiazox and 0.14–0.15 for bifenazate indicating degradation of the residues. However, the PF value varies between 1.13–1.64 for hexythiazox and 0.94–1.12 for bifenazate during the drying process indicating concentration of the residues in drying. The dietary exposure on each sampling day was less than the respective maximum permissible intake (MPI). The residues in market samples of raisins were devoid of any risk of acute toxicity related to dietary exposure. The PF value generated will be useful for the field level management of residues in grape intended for raisin preparation.
doi_str_mv 10.1007/s11356-020-10169-5
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The extraction method involved liquid-liquid extraction with ethyl acetate and dSPE cleanup with primary secondary amine (PSA). The drying of grape to raisin may increase or decrease residues of pesticides. During the raisin making process, the dissipation of residue was evaluated and the processing factor (PF) was established for drying. Dissipation data were best fitted to 1 st + 1 st -order kinetics with a half-life ranging between 6–10 days for hexythiazox and 5–6 days for bifenazate. The PF value for overall raisin making was found to be 0.20–0.36 for hexythiazox and 0.14–0.15 for bifenazate indicating degradation of the residues. However, the PF value varies between 1.13–1.64 for hexythiazox and 0.94–1.12 for bifenazate during the drying process indicating concentration of the residues in drying. The dietary exposure on each sampling day was less than the respective maximum permissible intake (MPI). The residues in market samples of raisins were devoid of any risk of acute toxicity related to dietary exposure. The PF value generated will be useful for the field level management of residues in grape intended for raisin preparation.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>32700274</pmid><doi>10.1007/s11356-020-10169-5</doi><tpages>8</tpages></addata></record>
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subjects Acetic acid
Acute toxicity
Aquatic Pollution
Atmospheric Protection/Air Quality Control/Air Pollution
Berries
Carbamates
Chemicals
Chromatography, Liquid
Dissipation factor
Drying
Earth and Environmental Science
Ecotoxicology
Environment
Environmental Chemistry
Environmental Health
Environmental science
Ethyl acetate
Evaluation
Experiments
Fruits
Grapes
Harvest
Hexythiazox
Hydrazines
Insecticides
Liquid chromatography
Liquid-liquid extraction
Mass spectrometry
Mass spectroscopy
Pesticide residues
Pesticide Residues - analysis
Pesticides
Raisins
Research Article
Residues
Tandem Mass Spectrometry
Thiazolidines
Toxicity
Vitis
Waste Water Technology
Water Management
Water Pollution Control
title Residue dissipation, evaluation of processing factor and safety assessment of hexythiazox and bifenazate residues during drying of grape to raisin
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