The Autism‐Related lncRNA MSNP1AS Regulates Moesin Protein to Influence the RhoA, Rac1, and PI3K/Akt Pathways and Regulate the Structure and Survival of Neurons

Autism spectrum disorder (ASD) is a complex disease involving multiple genes and multiple sites, and it is closely related to environmental factors. It has been gradually revealed that long noncoding RNAs (lncRNAs) may regulate the pathogenesis of ASD at the epigenetic level. In neuronal cells, the...

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Veröffentlicht in:	Autism research 2020-12, Vol.13 (12), p.2073-2082
Hauptverfasser:	Luo, Ting, Ou, Jin‐Nan, Cao, Li‐Fang, Peng, Xiao‐Qing, Li, Ya‐Min, Tian, Yong‐Quan
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase AKT protein Apoptosis Autism autism spectrum disorder Axons Cell viability Central nervous system Environmental factors Epigenetics lncRNA Moesin MSNP1AS Neurodevelopmental disorders neuron Neurons Pathogenesis Protein expression Proteins Rac1 protein RhoA protein Ribonucleic acid RNA Social factors Social interactions Survival
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