Conventional type 1 dendritic cells induce TH1, TH1‐like follicular helper T cells and regulatory T cells after antigen boost via DEC205 receptor

Conventional dendritic cells (cDCs) are specialized in antigen presentation. In the mouse spleen, cDCs are classified in cDC1s and cDC2s, and express DEC205 and DCIR2 endocytic receptors, respectively. Monoclonal antibodies (mAbs) αDEC205 (αDEC) and αDCIR2 have been fused to different antigens to de...

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Veröffentlicht in:	European journal of immunology 2020-12, Vol.50 (12), p.1895-1911
Hauptverfasser:	Sulczewski, Fernando Bandeira, Martino, Larissa Alves, Almeida, Bianca da Silva, Zaneti, Arthur Baruel, Ferreira, Natália Soares, Amorim, Kelly Nazaré da Silva, Yamamoto, Márcio Massao, Apostolico, Juliana de Souza, Rosa, Daniela Santoro, Boscardin, Silvia Beatriz
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibody response Antigen presentation antigen targeting Antigens Cell differentiation Class switching DCIR2 DEC205 Dendritic cells Immunization Immunoglobulin G Immunoregulation Inflammation Lymphocytes Lymphocytes T Monoclonal antibodies Poly (I:C) Spleen
Online-Zugang:	Volltext
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