Progress in Electrochemical Trifluoromethylation Reactions

The importance of fluorinated organic molecules in drugs and pharmaceuticals led to the development of several synthetic methods for introducing fluorine into bioactive molecules and trifluoromethylation is one of the key approaches for the same. Electrochemical organic synthesis has emerged as one...

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Veröffentlicht in:	Advanced synthesis & catalysis 2020-12, Vol.362 (23), p.5219-5237
Hauptverfasser:	Bhaskaran, Rasmi P., Babu, Beneesh P.
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Sprache:	eng
Schlagworte:	Chemical compounds Chemical reactions Clean energy Electrolysis Electroorganic synthesis Fluorine Literature reviews Organic chemistry Organic compounds Oxidation Reduction Trifluoromethylation
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description	The importance of fluorinated organic molecules in drugs and pharmaceuticals led to the development of several synthetic methods for introducing fluorine into bioactive molecules and trifluoromethylation is one of the key approaches for the same. Electrochemical organic synthesis has emerged as one of the most sustainable, green synthetic strategies in recent years and new developments in electroorganic synthesis also focus on electrochemical trifluoromethylation of organic compounds. A considerable number of reports have appeared in recent literature and this review surveys all the recent developments in electrochemical trifluoromethylation reactions. This highly sustainable trifluoromethylating protocol will emerge further soon and pave the way for more energy‐efficient and green protocols.
doi_str_mv	10.1002/adsc.202000996
format	Article
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subjects	Chemical compounds Chemical reactions Clean energy Electrolysis Electroorganic synthesis Fluorine Literature reviews Organic chemistry Organic compounds Oxidation Reduction Trifluoromethylation
title	Progress in Electrochemical Trifluoromethylation Reactions
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