Nickel‐Catalyzed Direct Trifluoroethylation of Aryl Iodides with 1,1,1‐Trifluoro‐2‐Iodoethane via Reductive Coupling

A nickel‐catalyzed direct trifluoroethylation of aryl iodides with an industrial raw material CF3CH2I has been developed, demonstrating high efficiency, excellent functional‐group compatibility, especially with large sterically hindered groups. The key to success is the combination of nickel with re...

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Veröffentlicht in:	Advanced synthesis & catalysis 2020-12, Vol.362 (23), p.5363-5367
Hauptverfasser:	Li, Han, Sheng, Jie, Liao, Guang‐Xu, Wu, Bing‐Bing, Ni, Hui‐Qi, Li, Yan, Wang, Xi‐Sheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Aromatic compounds aryl halides Biocompatibility Coupling (molecular) C−C coupling Iodides Nickel Phosphines radical reactions reductive coupling
Online-Zugang:	Volltext
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