Accuracy in tumor size measurements: Comparison of digital mammography, digital breast tomosynthesis and synthetic mammography
The aim of this study was to assess the accuracy of digital mammography (DM), digital breast tomosynthesis (DBT) and synthetic mammography (SM) in tumor size measurements compared with histological tumor sizes. 71 breast cancer patients who underwent DM and DBT acquisitions simultaneously were inclu...
Gespeichert in:
| Veröffentlicht in: | Clinical imaging 2021-01, Vol.69, p.115-119 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 119 |
|---|---|
| container_issue | |
| container_start_page | 115 |
| container_title | Clinical imaging |
| container_volume | 69 |
| creator | Şendur, Halit Nahit Cerit, Mahi Nur Gültekin, Serap Cindil, Emetullah Avdan Aslan, Aydan Erdal, Zeynep Sezgi Gültekin, Işıl İmge Teke, Furkan |
| description | The aim of this study was to assess the accuracy of digital mammography (DM), digital breast tomosynthesis (DBT) and synthetic mammography (SM) in tumor size measurements compared with histological tumor sizes.
71 breast cancer patients who underwent DM and DBT acquisitions simultaneously were included in this study. One radiologist with 8 years of experience in breast imaging measured tumor sizes independently in three separate sessions which include DM, DBT and SM images, respectively. The correlations between the measured tumor sizes on each imaging technique and histological sizes were analyzed using Spearman correlation test. The patients were categorized into two subgroups according to assigned breast density categories (dense and non-dense), and histological tumor sizes (≤2 cm and > 2 cm). To assess the agreement levels between the measured tumor sizes and histological sizes Bland-Altman analyses were performed for each imaging technique.
The mean of histological size of tumors was 23.85 ± 16.57 mm (median: 20). The means of measured tumor sizes were 21.21 ± 13.59 mm (median: 19), 21.52 ± 13.42 mm (median: 19) and 18.97 ± 11.21 mm (median: 17) in DM, DBT and SM, respectively. The Spearman correlation values with histologic sizes were 0.814 (P |
| doi_str_mv | 10.1016/j.clinimag.2020.07.004 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_journals_2467333763</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0899707120302679</els_id><sourcerecordid>2467333763</sourcerecordid><originalsourceid>FETCH-LOGICAL-c396t-4ad021fbd838e36aa65b0734ae9f4eaca4e5e06c1368f8a54e43e0d1eb0791db3</originalsourceid><addsrcrecordid>eNqNkU2P0zAQhiMEYsvCX1hZ4oIEKePYtRNOrKrlQ1qJC5wtx5l0XdV2sR1QOfDb11W6FeICJ49HzzOy562qKwpLClS83S7Nznrr9GbZQANLkEsA_qha0FaymvOue1wtoO26WoKkF9WzlLZQxI7Lp9UFaySVK9Yuqt_XxkxRmwOxnuTJhUiS_YXEoU5TRIc-p3dkHdxeR5uCJ2Ekg93YrHfEaefCJur93eHNudnHYmaSgwvp4PMdJpuI9gOZb9maP73n1ZNR7xK-OJ2X1bcPN1_Xn-rbLx8_r69va8M6kWuuB2jo2A8ta5EJrcWqB8m4xm7kqI3muEIQhjLRjq1eceQMYaBYqI4OPbusXs1z9zF8nzBl5WwyuNtpj2FKquFNC4K1DSvoy7_QbZiiL68rlJCMMSmOlJgpE0NKEUe1jyWNeFAU1DEhtVUPCaljQgqkKgkV8eo0fuodDmftIZICtDPwE_swJmPRGzxjACCAF5CWisp12Xm2wa_D5HNRX_-_Wuj3M41l8T8sRnUyBhvRZDUE-6_P3ANezMki</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2467333763</pqid></control><display><type>article</type><title>Accuracy in tumor size measurements: Comparison of digital mammography, digital breast tomosynthesis and synthetic mammography</title><source>MEDLINE</source><source>Web of Science - Science Citation Index Expanded - 2021<img src="https://exlibris-pub.s3.amazonaws.com/fromwos-v2.jpg" /></source><source>Access via ScienceDirect (Elsevier)</source><creator>Şendur, Halit Nahit ; Cerit, Mahi Nur ; Gültekin, Serap ; Cindil, Emetullah ; Avdan Aslan, Aydan ; Erdal, Zeynep Sezgi ; Gültekin, Işıl İmge ; Teke, Furkan</creator><creatorcontrib>Şendur, Halit Nahit ; Cerit, Mahi Nur ; Gültekin, Serap ; Cindil, Emetullah ; Avdan Aslan, Aydan ; Erdal, Zeynep Sezgi ; Gültekin, Işıl İmge ; Teke, Furkan</creatorcontrib><description>The aim of this study was to assess the accuracy of digital mammography (DM), digital breast tomosynthesis (DBT) and synthetic mammography (SM) in tumor size measurements compared with histological tumor sizes.
71 breast cancer patients who underwent DM and DBT acquisitions simultaneously were included in this study. One radiologist with 8 years of experience in breast imaging measured tumor sizes independently in three separate sessions which include DM, DBT and SM images, respectively. The correlations between the measured tumor sizes on each imaging technique and histological sizes were analyzed using Spearman correlation test. The patients were categorized into two subgroups according to assigned breast density categories (dense and non-dense), and histological tumor sizes (≤2 cm and > 2 cm). To assess the agreement levels between the measured tumor sizes and histological sizes Bland-Altman analyses were performed for each imaging technique.
The mean of histological size of tumors was 23.85 ± 16.57 mm (median: 20). The means of measured tumor sizes were 21.21 ± 13.59 mm (median: 19), 21.52 ± 13.42 mm (median: 19) and 18.97 ± 11.21 mm (median: 17) in DM, DBT and SM, respectively. The Spearman correlation values with histologic sizes were 0.814 (P < 0.001), 0.887 (P < 0.001), and 0.852 (P < 0.001) for DM, DBT and SM, respectively. In subgroup analyses, the correlation values showed decrement for tumors >2 cm in size compared to tumors ≤2 cm in size.
DBT provides the most accurate tumor size measurements among mammographic imaging techniques and if mammography will be used in tumor size measurements, DBT should be preferred.
•DBT provides the most accurate tumor size measurements.•DBT demonstrated the highest correlation with histological tumor sizes.•The correlation values show decrement for tumors above 2 cm in size.•Breast density did not affect the accuracy of tumor size measurements.</description><identifier>ISSN: 0899-7071</identifier><identifier>EISSN: 1873-4499</identifier><identifier>DOI: 10.1016/j.clinimag.2020.07.004</identifier><identifier>PMID: 32717538</identifier><language>eng</language><publisher>NEW YORK: Elsevier Inc</publisher><subject>Accuracy ; Breast - diagnostic imaging ; Breast cancer ; Breast Density ; Breast Neoplasms - diagnostic imaging ; Cancer therapies ; Correlation analysis ; Digital breast tomosynthesis ; Digital mammography ; Humans ; Imaging techniques ; Life Sciences & Biomedicine ; Mammography ; Medical imaging ; Radiology, Nuclear Medicine & Medical Imaging ; Science & Technology ; Subgroups ; Surgery ; Synthetic mammography ; Tumor size ; Tumors</subject><ispartof>Clinical imaging, 2021-01, Vol.69, p.115-119</ispartof><rights>2020 Elsevier Inc.</rights><rights>Copyright © 2020 Elsevier Inc. All rights reserved.</rights><rights>2020. Elsevier Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>true</woscitedreferencessubscribed><woscitedreferencescount>3</woscitedreferencescount><woscitedreferencesoriginalsourcerecordid>wos000604753100017</woscitedreferencesoriginalsourcerecordid><citedby>FETCH-LOGICAL-c396t-4ad021fbd838e36aa65b0734ae9f4eaca4e5e06c1368f8a54e43e0d1eb0791db3</citedby><cites>FETCH-LOGICAL-c396t-4ad021fbd838e36aa65b0734ae9f4eaca4e5e06c1368f8a54e43e0d1eb0791db3</cites><orcidid>0000-0002-9345-1577 ; 0000-0003-2878-6052</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.clinimag.2020.07.004$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>315,781,785,3551,27929,27930,39263,46000</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32717538$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Şendur, Halit Nahit</creatorcontrib><creatorcontrib>Cerit, Mahi Nur</creatorcontrib><creatorcontrib>Gültekin, Serap</creatorcontrib><creatorcontrib>Cindil, Emetullah</creatorcontrib><creatorcontrib>Avdan Aslan, Aydan</creatorcontrib><creatorcontrib>Erdal, Zeynep Sezgi</creatorcontrib><creatorcontrib>Gültekin, Işıl İmge</creatorcontrib><creatorcontrib>Teke, Furkan</creatorcontrib><title>Accuracy in tumor size measurements: Comparison of digital mammography, digital breast tomosynthesis and synthetic mammography</title><title>Clinical imaging</title><addtitle>CLIN IMAG</addtitle><addtitle>Clin Imaging</addtitle><description>The aim of this study was to assess the accuracy of digital mammography (DM), digital breast tomosynthesis (DBT) and synthetic mammography (SM) in tumor size measurements compared with histological tumor sizes.
71 breast cancer patients who underwent DM and DBT acquisitions simultaneously were included in this study. One radiologist with 8 years of experience in breast imaging measured tumor sizes independently in three separate sessions which include DM, DBT and SM images, respectively. The correlations between the measured tumor sizes on each imaging technique and histological sizes were analyzed using Spearman correlation test. The patients were categorized into two subgroups according to assigned breast density categories (dense and non-dense), and histological tumor sizes (≤2 cm and > 2 cm). To assess the agreement levels between the measured tumor sizes and histological sizes Bland-Altman analyses were performed for each imaging technique.
The mean of histological size of tumors was 23.85 ± 16.57 mm (median: 20). The means of measured tumor sizes were 21.21 ± 13.59 mm (median: 19), 21.52 ± 13.42 mm (median: 19) and 18.97 ± 11.21 mm (median: 17) in DM, DBT and SM, respectively. The Spearman correlation values with histologic sizes were 0.814 (P < 0.001), 0.887 (P < 0.001), and 0.852 (P < 0.001) for DM, DBT and SM, respectively. In subgroup analyses, the correlation values showed decrement for tumors >2 cm in size compared to tumors ≤2 cm in size.
DBT provides the most accurate tumor size measurements among mammographic imaging techniques and if mammography will be used in tumor size measurements, DBT should be preferred.
•DBT provides the most accurate tumor size measurements.•DBT demonstrated the highest correlation with histological tumor sizes.•The correlation values show decrement for tumors above 2 cm in size.•Breast density did not affect the accuracy of tumor size measurements.</description><subject>Accuracy</subject><subject>Breast - diagnostic imaging</subject><subject>Breast cancer</subject><subject>Breast Density</subject><subject>Breast Neoplasms - diagnostic imaging</subject><subject>Cancer therapies</subject><subject>Correlation analysis</subject><subject>Digital breast tomosynthesis</subject><subject>Digital mammography</subject><subject>Humans</subject><subject>Imaging techniques</subject><subject>Life Sciences & Biomedicine</subject><subject>Mammography</subject><subject>Medical imaging</subject><subject>Radiology, Nuclear Medicine & Medical Imaging</subject><subject>Science & Technology</subject><subject>Subgroups</subject><subject>Surgery</subject><subject>Synthetic mammography</subject><subject>Tumor size</subject><subject>Tumors</subject><issn>0899-7071</issn><issn>1873-4499</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>HGBXW</sourceid><sourceid>EIF</sourceid><recordid>eNqNkU2P0zAQhiMEYsvCX1hZ4oIEKePYtRNOrKrlQ1qJC5wtx5l0XdV2sR1QOfDb11W6FeICJ49HzzOy562qKwpLClS83S7Nznrr9GbZQANLkEsA_qha0FaymvOue1wtoO26WoKkF9WzlLZQxI7Lp9UFaySVK9Yuqt_XxkxRmwOxnuTJhUiS_YXEoU5TRIc-p3dkHdxeR5uCJ2Ekg93YrHfEaefCJur93eHNudnHYmaSgwvp4PMdJpuI9gOZb9maP73n1ZNR7xK-OJ2X1bcPN1_Xn-rbLx8_r69va8M6kWuuB2jo2A8ta5EJrcWqB8m4xm7kqI3muEIQhjLRjq1eceQMYaBYqI4OPbusXs1z9zF8nzBl5WwyuNtpj2FKquFNC4K1DSvoy7_QbZiiL68rlJCMMSmOlJgpE0NKEUe1jyWNeFAU1DEhtVUPCaljQgqkKgkV8eo0fuodDmftIZICtDPwE_swJmPRGzxjACCAF5CWisp12Xm2wa_D5HNRX_-_Wuj3M41l8T8sRnUyBhvRZDUE-6_P3ANezMki</recordid><startdate>202101</startdate><enddate>202101</enddate><creator>Şendur, Halit Nahit</creator><creator>Cerit, Mahi Nur</creator><creator>Gültekin, Serap</creator><creator>Cindil, Emetullah</creator><creator>Avdan Aslan, Aydan</creator><creator>Erdal, Zeynep Sezgi</creator><creator>Gültekin, Işıl İmge</creator><creator>Teke, Furkan</creator><general>Elsevier Inc</general><general>Elsevier</general><general>Elsevier Limited</general><scope>BLEPL</scope><scope>DTL</scope><scope>HGBXW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>M7Z</scope><scope>P64</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-9345-1577</orcidid><orcidid>https://orcid.org/0000-0003-2878-6052</orcidid></search><sort><creationdate>202101</creationdate><title>Accuracy in tumor size measurements: Comparison of digital mammography, digital breast tomosynthesis and synthetic mammography</title><author>Şendur, Halit Nahit ; Cerit, Mahi Nur ; Gültekin, Serap ; Cindil, Emetullah ; Avdan Aslan, Aydan ; Erdal, Zeynep Sezgi ; Gültekin, Işıl İmge ; Teke, Furkan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c396t-4ad021fbd838e36aa65b0734ae9f4eaca4e5e06c1368f8a54e43e0d1eb0791db3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Accuracy</topic><topic>Breast - diagnostic imaging</topic><topic>Breast cancer</topic><topic>Breast Density</topic><topic>Breast Neoplasms - diagnostic imaging</topic><topic>Cancer therapies</topic><topic>Correlation analysis</topic><topic>Digital breast tomosynthesis</topic><topic>Digital mammography</topic><topic>Humans</topic><topic>Imaging techniques</topic><topic>Life Sciences & Biomedicine</topic><topic>Mammography</topic><topic>Medical imaging</topic><topic>Radiology, Nuclear Medicine & Medical Imaging</topic><topic>Science & Technology</topic><topic>Subgroups</topic><topic>Surgery</topic><topic>Synthetic mammography</topic><topic>Tumor size</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Şendur, Halit Nahit</creatorcontrib><creatorcontrib>Cerit, Mahi Nur</creatorcontrib><creatorcontrib>Gültekin, Serap</creatorcontrib><creatorcontrib>Cindil, Emetullah</creatorcontrib><creatorcontrib>Avdan Aslan, Aydan</creatorcontrib><creatorcontrib>Erdal, Zeynep Sezgi</creatorcontrib><creatorcontrib>Gültekin, Işıl İmge</creatorcontrib><creatorcontrib>Teke, Furkan</creatorcontrib><collection>Web of Science Core Collection</collection><collection>Science Citation Index Expanded</collection><collection>Web of Science - Science Citation Index Expanded - 2021</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biochemistry Abstracts 1</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical imaging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Şendur, Halit Nahit</au><au>Cerit, Mahi Nur</au><au>Gültekin, Serap</au><au>Cindil, Emetullah</au><au>Avdan Aslan, Aydan</au><au>Erdal, Zeynep Sezgi</au><au>Gültekin, Işıl İmge</au><au>Teke, Furkan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Accuracy in tumor size measurements: Comparison of digital mammography, digital breast tomosynthesis and synthetic mammography</atitle><jtitle>Clinical imaging</jtitle><stitle>CLIN IMAG</stitle><addtitle>Clin Imaging</addtitle><date>2021-01</date><risdate>2021</risdate><volume>69</volume><spage>115</spage><epage>119</epage><pages>115-119</pages><issn>0899-7071</issn><eissn>1873-4499</eissn><abstract>The aim of this study was to assess the accuracy of digital mammography (DM), digital breast tomosynthesis (DBT) and synthetic mammography (SM) in tumor size measurements compared with histological tumor sizes.
71 breast cancer patients who underwent DM and DBT acquisitions simultaneously were included in this study. One radiologist with 8 years of experience in breast imaging measured tumor sizes independently in three separate sessions which include DM, DBT and SM images, respectively. The correlations between the measured tumor sizes on each imaging technique and histological sizes were analyzed using Spearman correlation test. The patients were categorized into two subgroups according to assigned breast density categories (dense and non-dense), and histological tumor sizes (≤2 cm and > 2 cm). To assess the agreement levels between the measured tumor sizes and histological sizes Bland-Altman analyses were performed for each imaging technique.
The mean of histological size of tumors was 23.85 ± 16.57 mm (median: 20). The means of measured tumor sizes were 21.21 ± 13.59 mm (median: 19), 21.52 ± 13.42 mm (median: 19) and 18.97 ± 11.21 mm (median: 17) in DM, DBT and SM, respectively. The Spearman correlation values with histologic sizes were 0.814 (P < 0.001), 0.887 (P < 0.001), and 0.852 (P < 0.001) for DM, DBT and SM, respectively. In subgroup analyses, the correlation values showed decrement for tumors >2 cm in size compared to tumors ≤2 cm in size.
DBT provides the most accurate tumor size measurements among mammographic imaging techniques and if mammography will be used in tumor size measurements, DBT should be preferred.
•DBT provides the most accurate tumor size measurements.•DBT demonstrated the highest correlation with histological tumor sizes.•The correlation values show decrement for tumors above 2 cm in size.•Breast density did not affect the accuracy of tumor size measurements.</abstract><cop>NEW YORK</cop><pub>Elsevier Inc</pub><pmid>32717538</pmid><doi>10.1016/j.clinimag.2020.07.004</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0002-9345-1577</orcidid><orcidid>https://orcid.org/0000-0003-2878-6052</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0899-7071 |
| ispartof | Clinical imaging, 2021-01, Vol.69, p.115-119 |
| issn | 0899-7071 1873-4499 |
| language | eng |
| recordid | cdi_proquest_journals_2467333763 |
| source | MEDLINE; Web of Science - Science Citation Index Expanded - 2021<img src="https://exlibris-pub.s3.amazonaws.com/fromwos-v2.jpg" />; Access via ScienceDirect (Elsevier) |
| subjects | Accuracy Breast - diagnostic imaging Breast cancer Breast Density Breast Neoplasms - diagnostic imaging Cancer therapies Correlation analysis Digital breast tomosynthesis Digital mammography Humans Imaging techniques Life Sciences & Biomedicine Mammography Medical imaging Radiology, Nuclear Medicine & Medical Imaging Science & Technology Subgroups Surgery Synthetic mammography Tumor size Tumors |
| title | Accuracy in tumor size measurements: Comparison of digital mammography, digital breast tomosynthesis and synthetic mammography |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-16T09%3A09%3A19IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Accuracy%20in%20tumor%20size%20measurements:%20Comparison%20of%20digital%20mammography,%20digital%20breast%20tomosynthesis%20and%20synthetic%20mammography&rft.jtitle=Clinical%20imaging&rft.au=%C5%9Eendur,%20Halit%20Nahit&rft.date=2021-01&rft.volume=69&rft.spage=115&rft.epage=119&rft.pages=115-119&rft.issn=0899-7071&rft.eissn=1873-4499&rft_id=info:doi/10.1016/j.clinimag.2020.07.004&rft_dat=%3Cproquest_pubme%3E2467333763%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2467333763&rft_id=info:pmid/32717538&rft_els_id=S0899707120302679&rfr_iscdi=true |