Tissue Engineering: Controlled Apoptosis of Stromal Cells to Engineer Human Microlivers (Adv. Funct. Mater. 48/2020)

Tissue Engineering: Controlled Apoptosis of Stromal Cells to Engineer Human Microlivers (Adv. Funct. Mater. 48/2020)

Tools are limited in resolving the dynamic contributions of multicellular interactions in bioengineered tissues. In article number 1910442, Sangeeta N. Bhatia and co‐workers present CAMEO (controlled apoptosis in multicellular tissues for engineering organogenesis) as a strategy to precisely manipul...

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Veröffentlicht in:Advanced functional materials 2020-11, Vol.30 (48), p.n/a
Hauptverfasser: Chen, Amanda X., Chhabra, Arnav, Song, Hyun‐Ho Greco, Fleming, Heather E., Chen, Christopher S., Bhatia, Sangeeta N.
Format: Artikel
Sprache:eng
Schlagworte:
Apoptosis
Bioengineering
biomedical applications
Fibroblasts
hydrogels
Materials science
Tissue engineering
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Zusammenfassung:Tools are limited in resolving the dynamic contributions of multicellular interactions in bioengineered tissues. In article number 1910442, Sangeeta N. Bhatia and co‐workers present CAMEO (controlled apoptosis in multicellular tissues for engineering organogenesis) as a strategy to precisely manipulate and study tissue composition. Herein, organoids comprised of hepatocytes (red) and fibroblasts (green) are used to glean new insights into 3D tissue biology.
ISSN:1616-301X
1616-3028
DOI:10.1002/adfm.202070317