APOE e4 Genotype Predicts Severe COVID-19 in the UK Biobank Community Cohort

The novel respiratory disease COVID-19 produces varying symptoms, with fever, cough, and shortness of breath being common. In older adults, it has been found that preexisting dementia is a major risk factor for COVID-19 severity in the UK Biobank (UKB). In another UK study of 16,749 patients hospita...

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Veröffentlicht in:	The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 2020-11, Vol.75 (11), p.2231-2232
Hauptverfasser:	Kuo, Chia-Ling, Pilling, Luke C, Atkins, Janice L, Masoli, Jane A H, Delgado, João, Kuchel, George A, Melzer, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Alzheimer's disease Apolipoprotein E4 Apolipoprotein E4 - genetics Betacoronavirus - physiology Biological Specimen Banks Comorbidity Coronavirus Infections - epidemiology Coronavirus Infections - genetics Coronavirus Infections - physiopathology Coronavirus Infections - virology Cough COVID-19 Delirium Dementia Dementia disorders England - epidemiology Female Fever Genetic Predisposition to Disease Genotypes Geriatrics & Gerontology Gerontology Homozygote Humans Life Sciences & Biomedicine Male Neurodegenerative diseases Older people Pandemics Pneumonia, Viral - epidemiology Pneumonia, Viral - genetics Pneumonia, Viral - physiopathology Pneumonia, Viral - virology Polymorphism, Single Nucleotide Respiratory diseases Risk factors SARS-CoV-2 Science & Technology Severity of Illness Index Survival Analysis THE JOURNAL OF GERONTOLOGY: Medical Sciences
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