Metal-organic framework based antibiotic release and antimicrobial response: an overview
Metal-organic frameworks (MOFs) are porous crystalline materials in which multidentate organic ligands and transition metal cations are linked via coordination bonds. The porosity of MOFs enables them to be used as drug carriers. Moreover, the presence of multiple coordination bonds makes them a des...
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Veröffentlicht in: | CrystEngComm 2020-11, Vol.22 (44), p.7513-7527 |
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creator | Kaur, Navpreet Tiwari, Pranav Kapoor, Kshipra S Saini, Anoop Kumar Sharma, Vinay Mobin, Shaikh M |
description | Metal-organic frameworks (MOFs) are porous crystalline materials in which multidentate organic ligands and transition metal cations are linked
via
coordination bonds. The porosity of MOFs enables them to be used as drug carriers. Moreover, the presence of multiple coordination bonds makes them a desirable candidate for sustainable release of drugs which is a prerequisite for the treatment of many chronic and virulent intracellular infections by bacteria. These properties of MOFs have been extensively studied and utilized in various antibacterial studies where MOFs were used as antibacterial drug carriers or they themselves showed antibacterial activity or in composite form with many other available antimicrobial nanomaterials. This review focuses on the recent advances in MOFs and MOF composites for antibacterial drug delivery in various biological systems.
MOF and MOF based heterostructures for antibacterial applications. |
doi_str_mv | 10.1039/d0ce01215g |
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via
coordination bonds. The porosity of MOFs enables them to be used as drug carriers. Moreover, the presence of multiple coordination bonds makes them a desirable candidate for sustainable release of drugs which is a prerequisite for the treatment of many chronic and virulent intracellular infections by bacteria. These properties of MOFs have been extensively studied and utilized in various antibacterial studies where MOFs were used as antibacterial drug carriers or they themselves showed antibacterial activity or in composite form with many other available antimicrobial nanomaterials. This review focuses on the recent advances in MOFs and MOF composites for antibacterial drug delivery in various biological systems.
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MOF and MOF based heterostructures for antibacterial applications.</description><subject>Antibiotics</subject><subject>Coordination</subject><subject>Drug carriers</subject><subject>Drug delivery systems</subject><subject>Metal-organic frameworks</subject><subject>Nanomaterials</subject><subject>Porosity</subject><subject>Porous materials</subject><subject>Transition metals</subject><issn>1466-8033</issn><issn>1466-8033</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNpNkM1LAzEQxYMoWKsX78KCN2F1kuxXvEmtVah46cHbkk0mJXW7qcm2xf_e6Ip6muG9HzOPR8g5hWsKXNxoUAiU0Xx5QEY0K4q0As4P_-3H5CSEFQDNKIUReX3GXrap80vZWZUYL9e4d_4taWRAnciut411fbQ8thi1KA3y2irvGivb6ISN6wLeRj1xO_Q7i_tTcmRkG_DsZ47J4mG6mDym85fZ0-Runiou8j7NdMydS9QsM1XeyJKpXKocWCYEqyjnhhowklWaS1FWWoBpeCMM50hBaz4ml8PZjXfvWwx9vXJb38WPNcsKKMsSiiJSVwMVI4fg0dQbb9fSf9QU6q_i6nuYTL-Lm0X4YoB9UL_cX7H8E6Y7ass</recordid><startdate>20201128</startdate><enddate>20201128</enddate><creator>Kaur, Navpreet</creator><creator>Tiwari, Pranav</creator><creator>Kapoor, Kshipra S</creator><creator>Saini, Anoop Kumar</creator><creator>Sharma, Vinay</creator><creator>Mobin, Shaikh M</creator><general>Royal Society of Chemistry</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7U5</scope><scope>8FD</scope><scope>L7M</scope><orcidid>https://orcid.org/0000-0003-1940-3822</orcidid><orcidid>https://orcid.org/0000-0001-7400-2867</orcidid></search><sort><creationdate>20201128</creationdate><title>Metal-organic framework based antibiotic release and antimicrobial response: an overview</title><author>Kaur, Navpreet ; Tiwari, Pranav ; Kapoor, Kshipra S ; Saini, Anoop Kumar ; Sharma, Vinay ; Mobin, Shaikh M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c395t-4d1035aed24f85ba72c5ac50249928133f1f0fa28d3a978d90fb3b9f33e10dd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Antibiotics</topic><topic>Coordination</topic><topic>Drug carriers</topic><topic>Drug delivery systems</topic><topic>Metal-organic frameworks</topic><topic>Nanomaterials</topic><topic>Porosity</topic><topic>Porous materials</topic><topic>Transition metals</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kaur, Navpreet</creatorcontrib><creatorcontrib>Tiwari, Pranav</creatorcontrib><creatorcontrib>Kapoor, Kshipra S</creatorcontrib><creatorcontrib>Saini, Anoop Kumar</creatorcontrib><creatorcontrib>Sharma, Vinay</creatorcontrib><creatorcontrib>Mobin, Shaikh M</creatorcontrib><collection>CrossRef</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>CrystEngComm</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kaur, Navpreet</au><au>Tiwari, Pranav</au><au>Kapoor, Kshipra S</au><au>Saini, Anoop Kumar</au><au>Sharma, Vinay</au><au>Mobin, Shaikh M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Metal-organic framework based antibiotic release and antimicrobial response: an overview</atitle><jtitle>CrystEngComm</jtitle><date>2020-11-28</date><risdate>2020</risdate><volume>22</volume><issue>44</issue><spage>7513</spage><epage>7527</epage><pages>7513-7527</pages><issn>1466-8033</issn><eissn>1466-8033</eissn><abstract>Metal-organic frameworks (MOFs) are porous crystalline materials in which multidentate organic ligands and transition metal cations are linked
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source | Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
subjects | Antibiotics Coordination Drug carriers Drug delivery systems Metal-organic frameworks Nanomaterials Porosity Porous materials Transition metals |
title | Metal-organic framework based antibiotic release and antimicrobial response: an overview |
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