Metal-organic framework based antibiotic release and antimicrobial response: an overview

Metal-organic frameworks (MOFs) are porous crystalline materials in which multidentate organic ligands and transition metal cations are linked via coordination bonds. The porosity of MOFs enables them to be used as drug carriers. Moreover, the presence of multiple coordination bonds makes them a des...

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Veröffentlicht in:CrystEngComm 2020-11, Vol.22 (44), p.7513-7527
Hauptverfasser: Kaur, Navpreet, Tiwari, Pranav, Kapoor, Kshipra S, Saini, Anoop Kumar, Sharma, Vinay, Mobin, Shaikh M
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container_issue 44
container_start_page 7513
container_title CrystEngComm
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creator Kaur, Navpreet
Tiwari, Pranav
Kapoor, Kshipra S
Saini, Anoop Kumar
Sharma, Vinay
Mobin, Shaikh M
description Metal-organic frameworks (MOFs) are porous crystalline materials in which multidentate organic ligands and transition metal cations are linked via coordination bonds. The porosity of MOFs enables them to be used as drug carriers. Moreover, the presence of multiple coordination bonds makes them a desirable candidate for sustainable release of drugs which is a prerequisite for the treatment of many chronic and virulent intracellular infections by bacteria. These properties of MOFs have been extensively studied and utilized in various antibacterial studies where MOFs were used as antibacterial drug carriers or they themselves showed antibacterial activity or in composite form with many other available antimicrobial nanomaterials. This review focuses on the recent advances in MOFs and MOF composites for antibacterial drug delivery in various biological systems. MOF and MOF based heterostructures for antibacterial applications.
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source Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection
subjects Antibiotics
Coordination
Drug carriers
Drug delivery systems
Metal-organic frameworks
Nanomaterials
Porosity
Porous materials
Transition metals
title Metal-organic framework based antibiotic release and antimicrobial response: an overview
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