Water‐Soluble Rhenium Clusters with Triazoles: The Effect of Chemical Structure on Cellular Internalization and the DNA Binding of the Complexes

Here we explore the effect of the nature of organic ligands in rhenium cluster complexes [Re6Q8L6]4− (where Q=S or Se, and L=benzotriazole, 1,2,3‐triazole or 1,2,4‐triazole) on the biological properties of the complexes, in particular on the cellular toxicity, cellular internalization and localizati...

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Veröffentlicht in:	Chemistry : a European journal 2020-11, Vol.26 (61), p.13904-13914
Hauptverfasser:	Konovalov, Dmitry I., Ivanov, Anton A., Frolova, Tatiana S., Eltsov, Ilia V., Gayfulin, Yakov M., Plunkett, Louis, Bazzar, Masoomeh, Adawi, Ali M., Bouillard, Jean‐Sebastien G., Baiborodin, Sergey I., Sinitsyna, Olga I., Kuratieva, Natalia V., Yanshole, Vadim V., Efremova, Olga A., Shestopalov, Michael A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antifungal agents Benzene Benzotriazole Binding Biological properties Cell Line Cellular structure Cervical cancer Cervix Chemistry Clusters Coordination Complexes - chemistry Coordination Complexes - pharmacokinetics Coordination compounds Cytotoxicity Deoxyribonucleic acid DNA DNA - chemistry DNA - metabolism DNA binding Electrochemical analysis Electrochemistry Fibroblasts Humans Hydrophobicity Internalization Ligands Localization Luminescence Rhenium Rhenium - chemistry rhenium clusters Structural analysis Toxicity Triazoles Triazoles - chemistry Triazoles - pharmacokinetics Water
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