Boosting the autophagy‐lysosomal pathway by phytochemicals: A potential therapeutic strategy against Alzheimer's disease

The lysosome is a membrane‐enclosed organelle in eukaryotic cells, which has basic pattern recognition for nutrient‐dependent signal transduction. In Alzheimer's disease, the already declining autophagy‐lysosomal function is exacerbated by an increased need for clearance of damaged proteins and...

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Veröffentlicht in:	IUBMB life 2020-11, Vol.72 (11), p.2360-2281
Hauptverfasser:	Nourbakhsh, Fahimeh, Read, Morgayn I., Barreto, George E., Sahebkar, Amirhossein
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Autophagy lysosomal dysfunction Lysosomes Natural products Neurodegenerative diseases Organelles Pathophysiology Pattern recognition Phagocytosis Phytochemicals Signal transduction
Online-Zugang:	Volltext
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