Dual‐Emissive Platinum(II) Metallacage with a Sensitive Oxygen Response for Imaging of Hypoxia and Imaging‐Guided Chemotherapy

Imaging of hypoxia in vivo helps with accurate cancer diagnosis and evaluation of therapeutic outcomes. A PtII metallacage with oxygen‐responsive red phosphorescence and steady fluorescence for in vivo hypoxia imaging and chemotherapy is reported. The therapeutic agent and diagnostic probe were inte...

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Veröffentlicht in:	Angewandte Chemie 2020-11, Vol.132 (45), p.20383-20389
Hauptverfasser:	Zhu, Huangtianzhi, Li, Qi, Shi, Bingbing, Ge, Fujing, Liu, Yuezhou, Mao, Zhengwei, Zhu, Hong, Wang, Sheng, Yu, Guocan, Huang, Feihe, Stang, Peter J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical materials Chemical compounds Chemistry Chemotherapy Diagnostic systems Fluorescence Hypoxia hypoxia imaging Medical imaging metallacages Nanoparticles Oxygen Pharmacology Phosphorescence Platinum self-assembly supramolecular chemistry
Online-Zugang:	Volltext
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