Succinic acid: a novel and efficient organo-catalyst for synthesis of α-amino nitriles under solvent free condition

A simple, efficient and eco-friendly general protocol has been developed for the synthesis of three-component reaction methodology of Strecker’s α-amino nitriles by using various aldehyde or ketone, amines and trimethylsilyl cyanide (TMS-CN). In this methodology, succinic acid is used as a novel and...

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Veröffentlicht in:	Organic communications 2020-07, Vol.13 (3), p.103-113
1. Verfasser:	Ghogare, Ramesh
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldehydes Amines Catalysts Chemical synthesis Cyanides Nitriles Room temperature Solvents Succinic acid
Online-Zugang:	Volltext
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