Combined cytotoxic and genotoxic effects of ochratoxin A and fumonisin B1 in human kidney and liver cell models

Food products can be contaminated by several fungi species and each species may produce different mycotoxins, leading to human combined exposure. Although predictions about the joint toxic effects of mycotoxins can be made from their individual toxicities, experimental data is still limited to allow...

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Veröffentlicht in:	Toxicology in vitro 2020-10, Vol.68, p.104949, Article 104949
Hauptverfasser:	Pinhão, M., Tavares, A.M., Loureiro, S., Louro, H., Alvito, P., Silva, M.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antagonism Bioassays Cell culture Cell lines Comet assay Cytotoxicity Damage detection Deoxyribonucleic acid DNA DNA damage Exposure Food contamination Fumonisin B1 Fungi Genotoxicity Hazard assessment Hepatocytes Interactive effects Kidneys Life Sciences & Biomedicine Liver Liver and kidney toxicity Mathematical models Mycotoxins Ochratoxin A Organs Science & Technology Toxicity Toxicology
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