Abdominal Mass Caused Failure to Thrive in a Young Boy: Mixed-Type Localized Retroperitoneal Castleman Disease
Castleman disease is a rare cause of retroperitoneal mass in children. Clinical presentation and laboratory findings are usually nonspecific. Imaging shows features of a hypervascular or soft tissue mass. We present a 12-year-old boy who complained of frequent colds, fatigue, and failure to gain wei...
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| Veröffentlicht in: | Case Reports in Oncology 2020-07, Vol.13 (2), p.853-856 |
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| creator | Ashjaei, Bahar Ghamari Khameneh, Afshar Darban Hosseini Amirkhiz, Gisoo |
| description | Castleman disease is a rare cause of retroperitoneal mass in children. Clinical presentation and laboratory findings are usually nonspecific. Imaging shows features of a hypervascular or soft tissue mass. We present a 12-year-old boy who complained of frequent colds, fatigue, and failure to gain weight for the past 4 years who was referred to our hospital. Anemia and hypergammaglobulinemia were revealed in laboratory tests. Imaging showed a well-delineated retroperitoneal soft tissue mass with intense homogenous enhancement at the midline below the aortic bifurcation. The histopathological features were consistent with mixed type unicentric Castleman disease. Surgical removal was curative. Our patient’s hematological abnormalities resolved, and he gained 10 kg in the next 4 weeks after the operation and reached the 25–50th percentile for his age. |
| doi_str_mv | 10.1159/000508531 |
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Clinical presentation and laboratory findings are usually nonspecific. Imaging shows features of a hypervascular or soft tissue mass. We present a 12-year-old boy who complained of frequent colds, fatigue, and failure to gain weight for the past 4 years who was referred to our hospital. Anemia and hypergammaglobulinemia were revealed in laboratory tests. Imaging showed a well-delineated retroperitoneal soft tissue mass with intense homogenous enhancement at the midline below the aortic bifurcation. The histopathological features were consistent with mixed type unicentric Castleman disease. Surgical removal was curative. Our patient’s hematological abnormalities resolved, and he gained 10 kg in the next 4 weeks after the operation and reached the 25–50th percentile for his age.</description><identifier>ISSN: 1662-6575</identifier><identifier>EISSN: 1662-6575</identifier><identifier>DOI: 10.1159/000508531</identifier><identifier>PMID: 32884530</identifier><language>eng</language><publisher>Basel, Switzerland: S. Karger AG</publisher><subject>Abdomen ; Age ; Anemia ; Asymptomatic ; Case Report ; Case reports ; Case studies ; castleman disease ; Diagnosis ; Failure to thrive ; Hematology ; Hyperplasia ; Laboratories ; Lymphatic system ; Lymphoma ; Lymphoproliferative disorders ; Medical imaging ; Patients ; pediatric ; Pediatric research ; Pediatrics ; Peritoneal diseases ; Plasma ; retroperitoneum ; Surgery</subject><ispartof>Case Reports in Oncology, 2020-07, Vol.13 (2), p.853-856</ispartof><rights>2020 The Author(s). Published by S. Karger AG, Basel</rights><rights>COPYRIGHT 2020 S. 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Clinical presentation and laboratory findings are usually nonspecific. Imaging shows features of a hypervascular or soft tissue mass. We present a 12-year-old boy who complained of frequent colds, fatigue, and failure to gain weight for the past 4 years who was referred to our hospital. Anemia and hypergammaglobulinemia were revealed in laboratory tests. Imaging showed a well-delineated retroperitoneal soft tissue mass with intense homogenous enhancement at the midline below the aortic bifurcation. The histopathological features were consistent with mixed type unicentric Castleman disease. Surgical removal was curative. Our patient’s hematological abnormalities resolved, and he gained 10 kg in the next 4 weeks after the operation and reached the 25–50th percentile for his age.</description><subject>Abdomen</subject><subject>Age</subject><subject>Anemia</subject><subject>Asymptomatic</subject><subject>Case Report</subject><subject>Case reports</subject><subject>Case studies</subject><subject>castleman disease</subject><subject>Diagnosis</subject><subject>Failure to thrive</subject><subject>Hematology</subject><subject>Hyperplasia</subject><subject>Laboratories</subject><subject>Lymphatic system</subject><subject>Lymphoma</subject><subject>Lymphoproliferative disorders</subject><subject>Medical imaging</subject><subject>Patients</subject><subject>pediatric</subject><subject>Pediatric research</subject><subject>Pediatrics</subject><subject>Peritoneal diseases</subject><subject>Plasma</subject><subject>retroperitoneum</subject><subject>Surgery</subject><issn>1662-6575</issn><issn>1662-6575</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>M--</sourceid><sourceid>BENPR</sourceid><sourceid>DOA</sourceid><recordid>eNptks9v0zAUxyMEYmNw4M7BEicOHXb8IzEHpBI2mNRp0lQOnKwX56VzSeNgJxPdX49Lq8Ik5IOt5-_3o6--eln2mtFzxqR-TymVtJScPclOmVL5TMlCPv3nfZK9iHFNqdJSyefZCc_LUkhOT7N-Xjd-43royDXESCqYIjbkElw3BSSjJ8u74O6RuJ4A-e6nfkU--e0Hcu1-YTNbbgckC2-hcw_Jdotj8AMGN_oeE7KCOHa4gZ58dhEh4svsWQtdxFeH-yz7dnmxrL7OFjdfrqr5YmZFqceZzkUhUKBlDaNtgSAxb2mupNUoNdMClFSMlTq3VtVQt6mGAnhTWKtLm7f8LLvacxsPazMEt4GwNR6c-TPwYWUgjM52aIAzjkxJxhsQwLEsEG3bCoBaCct0Yn3cs4ap3mBjsR8DdI-gj396d2dW_t4UQnBV5gnw9gAI_ueEcTRrP4VUeTS5EIVWXFOaVOd71QpSKte3PsFsOg1unE19ti7N54orzqkWO8O7vcEGH2PA9hiJUbPbC3Pci78RfkBYYTgqq9ubvcIMza61N_9VHSC_AfnMvgk</recordid><startdate>20200716</startdate><enddate>20200716</enddate><creator>Ashjaei, Bahar</creator><creator>Ghamari Khameneh, Afshar</creator><creator>Darban Hosseini Amirkhiz, Gisoo</creator><general>S. 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| subjects | Abdomen Age Anemia Asymptomatic Case Report Case reports Case studies castleman disease Diagnosis Failure to thrive Hematology Hyperplasia Laboratories Lymphatic system Lymphoma Lymphoproliferative disorders Medical imaging Patients pediatric Pediatric research Pediatrics Peritoneal diseases Plasma retroperitoneum Surgery |
| title | Abdominal Mass Caused Failure to Thrive in a Young Boy: Mixed-Type Localized Retroperitoneal Castleman Disease |
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