Novel Disinfection Byproducts Formed from the Pharmaceutical Gemfibrozil Are Bioaccumulative and Elicit Increased Toxicity Relative to the Parent Compound in Marine Polychaetes (Neanthes arenaceodentata)

Formation of halogenated disinfection byproducts (DBPs) from pharmaceutically active compounds has been observed in water supply systems following wastewater chlorination. Although research has been limited thus far, several studies have shown that halogenated DBPs may elicit increased toxicity comp...

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Veröffentlicht in:	Environmental science & technology 2020-09, Vol.54 (18), p.11127-11136
Hauptverfasser:	Andrzejczyk, Nicolette E, Greer, Justin B, Nelson, Eric, Zhang, Junqian, Rimoldi, John M, Gadepalli, Rama S. V, Edwards, Isaiah, Schlenk, Daniel
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute toxicity Animals Antiandrogens Bioaccumulation Biocompatibility Biota By products Byproducts Chlorination Contaminants in Aquatic and Terrestrial Environments Disinfectants Disinfection Exposure Food chains Food webs Gemfibrozil Gemfibrozil - toxicity Halogenation In vivo methods and tests Lipids Neanthes arenaceodentata Oryzias latipes Pharmaceutical Preparations Sediments Toxicity Toxicity testing Wastewater Water conveyance Water Pollutants, Chemical - analysis Water Pollutants, Chemical - toxicity Water Purification Water supply Water supply systems
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