Emerging landscape of circular RNAs as biomarkers and pivotal regulators in osteosarcoma

Osteosarcoma represents the most prevailing primary bone tumor and the third most common cancer in children and adolescents worldwide. Among noncoding RNAs, circular RNAs (circRNAs) refer to a unique class in the shape of a covalently closed continuous loop with neither 5′ caps nor 3′‐polyadenylated...

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Veröffentlicht in:	Journal of cellular physiology 2020-12, Vol.235 (12), p.9037-9058
Hauptverfasser:	Tu, Chao, He, Jieyu, Qi, Lin, Ren, Xiaolei, Zhang, Chenghao, Duan, Zhixi, Yang, Kexin, Wang, Wanchun, Lu, Qiong, Li, Zhihong
Format:	Artikel
Sprache:	eng
Schlagworte:	biomarker Biomarkers Biomarkers - analysis Biomarkers - metabolism Biomedical materials Bone cancer Bone tumors Cancer Carcinogenesis - genetics Chemoresistance Children circRNA exosomal circRNA Gene expression Gene sequencing Genomes Humans Immune response miRNA Osteosarcoma Osteosarcoma - genetics Osteosarcoma - pathology Polyadenylation Post-transcription prognosis Regulators RNA, Circular - genetics RNA, Circular - metabolism RNA, Messenger - metabolism RNA, Untranslated - genetics Sarcoma Splicing Tumorigenesis
Online-Zugang:	Volltext
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