Keratosis pilaris‐like eruption secondary to nilotinib in a child

Nilotinib is a new multitargeted tyrosine kinase inhibitor, which is used to treat chronic myelogenous leukemia when intolerance or recurrence to imatinib occurs. We report the case of a 14‐year‐old patient being treated with nilotinib who developed a keratosis pilaris‐like eruption. This cutaneous...

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Veröffentlicht in:Pediatric dermatology 2020-09, Vol.37 (5), p.968-969
Hauptverfasser: Oro‐Ayude, Marcos, Feito, Marta, Quintana‐Castanedo, Lucía, Beato‐Merino, Maria Jose, De Lucas, Raúl
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container_end_page 969
container_issue 5
container_start_page 968
container_title Pediatric dermatology
container_volume 37
creator Oro‐Ayude, Marcos
Feito, Marta
Quintana‐Castanedo, Lucía
Beato‐Merino, Maria Jose
De Lucas, Raúl
description Nilotinib is a new multitargeted tyrosine kinase inhibitor, which is used to treat chronic myelogenous leukemia when intolerance or recurrence to imatinib occurs. We report the case of a 14‐year‐old patient being treated with nilotinib who developed a keratosis pilaris‐like eruption. This cutaneous adverse effect is a rare but increasingly reported side effect of this therapy.
doi_str_mv 10.1111/pde.14267
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source MEDLINE; Access via Wiley Online Library
subjects Abnormalities, Multiple
Adolescent
Antineoplastic Agents
BCR‐ABL‐positive
Case reports
chronic
Chronic myeloid leukemia
Darier Disease
Enzyme inhibitors
Eyebrows - abnormalities
Fusion Proteins, bcr-abl
Humans
Imatinib
Inhibitor drugs
Intolerance
Keratosis
Leukemia
myelogenous
Myeloid leukemia
Pediatrics
protein kinase inhibitors
Protein Kinase Inhibitors - adverse effects
Protein-tyrosine kinase
Pyrimidines - adverse effects
Side effects
Skin diseases
Skin eruptions
Targeted cancer therapy
title Keratosis pilaris‐like eruption secondary to nilotinib in a child
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