Aligned PCL Fiber Conduits Immobilized with Nerve Growth Factor Gradients Enhance and Direct Sciatic Nerve Regeneration

Topographical guidance and chemotaxis are crucial factors for peripheral nerve regeneration. This study describes the preparation of highly aligned poly(ε‐caprolactone) (PCL) fiber conduits coated with a concentration gradient of nerve growth factor (NGF) (A/G‐PCL) using a newly designed electrospin...

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Veröffentlicht in:	Advanced functional materials 2020-09, Vol.30 (39), p.n/a
Hauptverfasser:	Zhu, Lei, Jia, Shuaijun, Liu, Tuanjiang, Yan, Liang, Huang, Dageng, Wang, Zhiyuan, Chen, Shi, Zhang, Zhengping, Zeng, Wen, Zhang, Ying, Yang, Hao, Hao, Dingjun
Format:	Artikel
Sprache:	eng
Schlagworte:	aligned nanofibers Attraction Axons Cell adhesion Cell adhesion & migration Concentration gradient electrospinning growth factor gradient Growth factors Materials science Muscles nerve guidance conduit peripheral nerve regeneration Regeneration
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