In vitro and in vivo toxicological evaluation of transition metal-doped titanium dioxide nanoparticles: Nickel and platinum

Transition metal-doped titanium dioxide nanoparticles (M-TiO2 NPs) have been studied to enhance the activity of TiO2 NPs in biomedical applications. In this study, in vitro and in vivo toxicological aspects of M-TiO2 NPs were reported to assess the safety of these materials. M-TiO2 NPs were synthesi...

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Veröffentlicht in:	Materials Science & Engineering C 2020-10, Vol.115, p.110843, Article 110843
Hauptverfasser:	Jin, Su-Eon, Kim, Eun-Ju, Kim, Hyunmin, Kim, Hyunzu, Hwang, Woochul, Hong, Seok Won
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine Alanine transaminase Alanine Transaminase - metabolism Animals Aspartate Aminotransferases - metabolism Aspartate transaminase Biocompatibility Biomedical materials Body weight Cell Line Cell size Cell Survival - drug effects Crystals Cytotoxicity Histology In vivo methods and tests Materials science Metal Nanoparticles - chemistry Metal Nanoparticles - toxicity Mice Models, Animal Nanoparticles Nickel Nickel - chemistry Phototoxicity Physicochemical properties Platinum Platinum - chemistry Skin Skin - drug effects Surgical implants Titanium Titanium - chemistry Titanium - pharmacology Titanium dioxide Titanium dioxide nanoparticles Toxicity Toxicity Tests Transaminase Transition metal-doping Transition metals
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