Extraction of Biological Hydroxyapatite from Bovine Bone for Biomedical Applications
Current biomedical field demands intensive research on cost-effective and high availability materials to fulfil its various applications. Owing to its similar characteristic to human bone, biological hydroxyapatite (HAp) has been used as an alternative in bone replacement and implantation. In this s...
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| Veröffentlicht in: | Materials science forum 2020-09, Vol.1010, p.579-583 |
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| creator | Lee, Tee Chuan Idris, Maizlinda Izwana Muhamad, Mimi Suliza Latif, Amirul Faiz Abdul Abdullah, Hasan Zuhudi Ramli, Nurfarah Diyana Mohd Pu'ad, Nor Atiqah Syafinaz |
| description | Current biomedical field demands intensive research on cost-effective and high availability materials to fulfil its various applications. Owing to its similar characteristic to human bone, biological hydroxyapatite (HAp) has been used as an alternative in bone replacement and implantation. In this study, biological HAp was extracted from bovine bones via calcination. Powders calcined at 700 °C and 900 °C showed the presence of HAp. The FESEM analysis shows that the irregular morphology emerged and the size was increasing as the calcination temperature increased. By increasing the temperature of 1100 °C, β-TCP started to develop and influenced the ratio of Ca/P. At 900 °C, the Ca/P ratio obtained was 1.70, and closest to the theoretical ratio of Ca/P. The presences of trace elements like Ca, Mg, Sr Na, K and Zn in all samples are proved via EDS analysis, and these elements help to enhance the bioactivity hence make it a good alternative in biomedical applications. |
| doi_str_mv | 10.4028/www.scientific.net/MSF.1010.579 |
| format | Article |
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Owing to its similar characteristic to human bone, biological hydroxyapatite (HAp) has been used as an alternative in bone replacement and implantation. In this study, biological HAp was extracted from bovine bones via calcination. Powders calcined at 700 °C and 900 °C showed the presence of HAp. The FESEM analysis shows that the irregular morphology emerged and the size was increasing as the calcination temperature increased. By increasing the temperature of 1100 °C, β-TCP started to develop and influenced the ratio of Ca/P. At 900 °C, the Ca/P ratio obtained was 1.70, and closest to the theoretical ratio of Ca/P. The presences of trace elements like Ca, Mg, Sr Na, K and Zn in all samples are proved via EDS analysis, and these elements help to enhance the bioactivity hence make it a good alternative in biomedical applications.</description><identifier>ISSN: 0255-5476</identifier><identifier>ISSN: 1662-9752</identifier><identifier>EISSN: 1662-9752</identifier><identifier>DOI: 10.4028/www.scientific.net/MSF.1010.579</identifier><language>eng</language><publisher>Pfaffikon: Trans Tech Publications Ltd</publisher><subject>Biomedical materials ; Bones ; Calcium ; Hydroxyapatite ; Implantation ; Magnesium ; Morphology ; Roasting ; Trace elements ; Zinc</subject><ispartof>Materials science forum, 2020-09, Vol.1010, p.579-583</ispartof><rights>2020 Trans Tech Publications Ltd</rights><rights>Copyright Trans Tech Publications Ltd. Sep 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3319-43d0f6c21efa68cbc19b416024840316d1f60e0b5d972f3b117b5ed44201341a3</citedby><cites>FETCH-LOGICAL-c3319-43d0f6c21efa68cbc19b416024840316d1f60e0b5d972f3b117b5ed44201341a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttps://www.scientific.net/Image/TitleCover/5946?width=600</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/2443928751?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>315,782,786,21398,21399,23265,27933,27934,33539,33712,34323,43668,43796,44076</link.rule.ids></links><search><creatorcontrib>Lee, Tee Chuan</creatorcontrib><creatorcontrib>Idris, Maizlinda Izwana</creatorcontrib><creatorcontrib>Muhamad, Mimi Suliza</creatorcontrib><creatorcontrib>Latif, Amirul Faiz Abdul</creatorcontrib><creatorcontrib>Abdullah, Hasan Zuhudi</creatorcontrib><creatorcontrib>Ramli, Nurfarah Diyana</creatorcontrib><creatorcontrib>Mohd Pu'ad, Nor Atiqah Syafinaz</creatorcontrib><title>Extraction of Biological Hydroxyapatite from Bovine Bone for Biomedical Applications</title><title>Materials science forum</title><description>Current biomedical field demands intensive research on cost-effective and high availability materials to fulfil its various applications. Owing to its similar characteristic to human bone, biological hydroxyapatite (HAp) has been used as an alternative in bone replacement and implantation. In this study, biological HAp was extracted from bovine bones via calcination. Powders calcined at 700 °C and 900 °C showed the presence of HAp. The FESEM analysis shows that the irregular morphology emerged and the size was increasing as the calcination temperature increased. By increasing the temperature of 1100 °C, β-TCP started to develop and influenced the ratio of Ca/P. At 900 °C, the Ca/P ratio obtained was 1.70, and closest to the theoretical ratio of Ca/P. The presences of trace elements like Ca, Mg, Sr Na, K and Zn in all samples are proved via EDS analysis, and these elements help to enhance the bioactivity hence make it a good alternative in biomedical applications.</description><subject>Biomedical materials</subject><subject>Bones</subject><subject>Calcium</subject><subject>Hydroxyapatite</subject><subject>Implantation</subject><subject>Magnesium</subject><subject>Morphology</subject><subject>Roasting</subject><subject>Trace elements</subject><subject>Zinc</subject><issn>0255-5476</issn><issn>1662-9752</issn><issn>1662-9752</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqNkE1PwjAYgBujiYj-hyUePA36ve1kgICYYDyI56brWi0Z62yHwL-3ExOuXvr28OR53zwAPCA4ohDn4_1-PwrK6qazxqpRo7vxy9tihGAEWFZcgAHiHKdFxvAlGEDMWMpoxq_BTQgbCAnKER-A9fzQeak665rEmWRqXe0-rJJ1sjxW3h2OspWd7XRivNsmU_dtGx1HfIzzPb7V1S8-ads6fnpRuAVXRtZB3_3NIXhfzNezZbp6fXqeTVapIgQVKSUVNFxhpI3kuSoVKkqKOMQ0p_E-XiHDoYYlq4oMG1IilJVMV5RiiAhFkgzB_cnbeve106ETG7fzTVwpMKWkwHnGUKQeT5TyLgSvjWi93Up_FAiKPqWIKcU5pYgpRUwp-pQipoyGyckQUzWh0-rzvOi_jh8TioWo</recordid><startdate>20200917</startdate><enddate>20200917</enddate><creator>Lee, Tee Chuan</creator><creator>Idris, Maizlinda Izwana</creator><creator>Muhamad, Mimi Suliza</creator><creator>Latif, Amirul Faiz Abdul</creator><creator>Abdullah, Hasan Zuhudi</creator><creator>Ramli, Nurfarah Diyana</creator><creator>Mohd Pu'ad, Nor Atiqah Syafinaz</creator><general>Trans Tech Publications Ltd</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7SR</scope><scope>7XB</scope><scope>88I</scope><scope>8BQ</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>JG9</scope><scope>KB.</scope><scope>M2P</scope><scope>PDBOC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope></search><sort><creationdate>20200917</creationdate><title>Extraction of Biological Hydroxyapatite from Bovine Bone for Biomedical Applications</title><author>Lee, Tee Chuan ; 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Owing to its similar characteristic to human bone, biological hydroxyapatite (HAp) has been used as an alternative in bone replacement and implantation. In this study, biological HAp was extracted from bovine bones via calcination. Powders calcined at 700 °C and 900 °C showed the presence of HAp. The FESEM analysis shows that the irregular morphology emerged and the size was increasing as the calcination temperature increased. By increasing the temperature of 1100 °C, β-TCP started to develop and influenced the ratio of Ca/P. At 900 °C, the Ca/P ratio obtained was 1.70, and closest to the theoretical ratio of Ca/P. The presences of trace elements like Ca, Mg, Sr Na, K and Zn in all samples are proved via EDS analysis, and these elements help to enhance the bioactivity hence make it a good alternative in biomedical applications.</abstract><cop>Pfaffikon</cop><pub>Trans Tech Publications Ltd</pub><doi>10.4028/www.scientific.net/MSF.1010.579</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Biomedical materials Bones Calcium Hydroxyapatite Implantation Magnesium Morphology Roasting Trace elements Zinc |
| title | Extraction of Biological Hydroxyapatite from Bovine Bone for Biomedical Applications |
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