Mechanochemical synthesis of (hetero)aryl Au() complexes
Growing demand for sustainable chemical syntheses casts mechanochemistry in a new light as an environmentally benign alternative to traditional solvent-based methods. Given recent interest in Au( i ) complexes for catalytic, materials, and medicinal applications, we developed a mechanochemical proto...
Gespeichert in:
| Veröffentlicht in: | Green chemistry : an international journal and green chemistry resource : GC 2020, Vol.22 (17), p.5648-5655 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 5655 |
|---|---|
| container_issue | 17 |
| container_start_page | 5648 |
| container_title | Green chemistry : an international journal and green chemistry resource : GC |
| container_volume | 22 |
| creator | Ingner, Fredric J. L Giustra, Zachary X Novosedlik, Sebastian Orthaber, Andreas Gates, Paul J Dyrager, Christine Pilarski, Lukasz T |
| description | Growing demand for sustainable chemical syntheses casts mechanochemistry in a new light as an environmentally benign alternative to traditional solvent-based methods. Given recent interest in Au(
i
) complexes for catalytic, materials, and medicinal applications, we developed a mechanochemical protocol to prepare (hetero)aryl Au(
i
) complexes under green conditions. The procedure reported here uses C-H or C-B activation to afford the corresponding Au(
i
) complexes in high yields. Our approach bypasses external heating, long reaction times and the use of toxic solvents. We demonstrate that mechanochemical C-H auration can be used on highly functionalised bioactive substrates. Mechanistic aspects of the C-H auration are discussed.
Shake, Rattle and Gold! Mechanochemistry enables the efficient and selective synthesis of organo-Au(
i
) complexes. |
| doi_str_mv | 10.1039/d0gc02263b |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2438576513</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2438576513</sourcerecordid><originalsourceid>FETCH-LOGICAL-c524t-7df7ea4fb29e32db2ab792223f494fc78fc3160cae90132f6e2e35d6579b7aae3</originalsourceid><addsrcrecordid>eNp9kMFLwzAUxosoOKcX70LFyyZWk5e0WY9z0ylMvKjXkKYva8e21KRF999brcybp_fg-_Hx8QuCU0quKWHpTU4WmgAkLNsLepQnLEpBkP3dn8BhcOT9khBKRcJ7wegJdaE2Vhe4LrVahX67qQv0pQ-tCQcF1ujsULntKhw3g2Go7bpa4Sf64-DAqJXHk9_bD17v714mD9H8efY4Gc8jHQOvI5EbgYqbDFJkkGegMpECADM85UaLkdGMJkQrTAllYBIEZHGexCLNhFLI-sFV1-s_sGoyWbly3c6RVpVyWr6NpXUL2TSSA3AOLX7R4ZWz7w36Wi5t4zbtQgmcjWKRxJS11GVHaWe9d2h2tZTIb5FySmaTH5G3LXzWwc7rHfcnus3P_8tllRv2BXrHedo</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2438576513</pqid></control><display><type>article</type><title>Mechanochemical synthesis of (hetero)aryl Au() complexes</title><source>Royal Society Of Chemistry Journals</source><source>SWEPUB Freely available online</source><source>Alma/SFX Local Collection</source><creator>Ingner, Fredric J. L ; Giustra, Zachary X ; Novosedlik, Sebastian ; Orthaber, Andreas ; Gates, Paul J ; Dyrager, Christine ; Pilarski, Lukasz T</creator><creatorcontrib>Ingner, Fredric J. L ; Giustra, Zachary X ; Novosedlik, Sebastian ; Orthaber, Andreas ; Gates, Paul J ; Dyrager, Christine ; Pilarski, Lukasz T</creatorcontrib><description>Growing demand for sustainable chemical syntheses casts mechanochemistry in a new light as an environmentally benign alternative to traditional solvent-based methods. Given recent interest in Au(
i
) complexes for catalytic, materials, and medicinal applications, we developed a mechanochemical protocol to prepare (hetero)aryl Au(
i
) complexes under green conditions. The procedure reported here uses C-H or C-B activation to afford the corresponding Au(
i
) complexes in high yields. Our approach bypasses external heating, long reaction times and the use of toxic solvents. We demonstrate that mechanochemical C-H auration can be used on highly functionalised bioactive substrates. Mechanistic aspects of the C-H auration are discussed.
Shake, Rattle and Gold! Mechanochemistry enables the efficient and selective synthesis of organo-Au(
i
) complexes.</description><identifier>ISSN: 1463-9262</identifier><identifier>ISSN: 1463-9270</identifier><identifier>EISSN: 1463-9270</identifier><identifier>DOI: 10.1039/d0gc02263b</identifier><language>eng</language><publisher>Cambridge: Royal Society of Chemistry</publisher><subject>Aromatic compounds ; Biocompatibility ; Crystallography ; Green chemistry ; NMR ; Nuclear magnetic resonance ; Solvents ; Substrates</subject><ispartof>Green chemistry : an international journal and green chemistry resource : GC, 2020, Vol.22 (17), p.5648-5655</ispartof><rights>Copyright Royal Society of Chemistry 2020</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c524t-7df7ea4fb29e32db2ab792223f494fc78fc3160cae90132f6e2e35d6579b7aae3</citedby><cites>FETCH-LOGICAL-c524t-7df7ea4fb29e32db2ab792223f494fc78fc3160cae90132f6e2e35d6579b7aae3</cites><orcidid>0000-0001-8619-7745 ; 0000-0001-5403-9902 ; 0000-0002-9353-2238 ; 0000-0001-5623-2837 ; 0000-0003-4647-9769</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,552,780,784,885,4024,27923,27924,27925</link.rule.ids><backlink>$$Uhttps://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-422442$$DView record from Swedish Publication Index$$Hfree_for_read</backlink></links><search><creatorcontrib>Ingner, Fredric J. L</creatorcontrib><creatorcontrib>Giustra, Zachary X</creatorcontrib><creatorcontrib>Novosedlik, Sebastian</creatorcontrib><creatorcontrib>Orthaber, Andreas</creatorcontrib><creatorcontrib>Gates, Paul J</creatorcontrib><creatorcontrib>Dyrager, Christine</creatorcontrib><creatorcontrib>Pilarski, Lukasz T</creatorcontrib><title>Mechanochemical synthesis of (hetero)aryl Au() complexes</title><title>Green chemistry : an international journal and green chemistry resource : GC</title><description>Growing demand for sustainable chemical syntheses casts mechanochemistry in a new light as an environmentally benign alternative to traditional solvent-based methods. Given recent interest in Au(
i
) complexes for catalytic, materials, and medicinal applications, we developed a mechanochemical protocol to prepare (hetero)aryl Au(
i
) complexes under green conditions. The procedure reported here uses C-H or C-B activation to afford the corresponding Au(
i
) complexes in high yields. Our approach bypasses external heating, long reaction times and the use of toxic solvents. We demonstrate that mechanochemical C-H auration can be used on highly functionalised bioactive substrates. Mechanistic aspects of the C-H auration are discussed.
Shake, Rattle and Gold! Mechanochemistry enables the efficient and selective synthesis of organo-Au(
i
) complexes.</description><subject>Aromatic compounds</subject><subject>Biocompatibility</subject><subject>Crystallography</subject><subject>Green chemistry</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>Solvents</subject><subject>Substrates</subject><issn>1463-9262</issn><issn>1463-9270</issn><issn>1463-9270</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>D8T</sourceid><recordid>eNp9kMFLwzAUxosoOKcX70LFyyZWk5e0WY9z0ylMvKjXkKYva8e21KRF999brcybp_fg-_Hx8QuCU0quKWHpTU4WmgAkLNsLepQnLEpBkP3dn8BhcOT9khBKRcJ7wegJdaE2Vhe4LrVahX67qQv0pQ-tCQcF1ujsULntKhw3g2Go7bpa4Sf64-DAqJXHk9_bD17v714mD9H8efY4Gc8jHQOvI5EbgYqbDFJkkGegMpECADM85UaLkdGMJkQrTAllYBIEZHGexCLNhFLI-sFV1-s_sGoyWbly3c6RVpVyWr6NpXUL2TSSA3AOLX7R4ZWz7w36Wi5t4zbtQgmcjWKRxJS11GVHaWe9d2h2tZTIb5FySmaTH5G3LXzWwc7rHfcnus3P_8tllRv2BXrHedo</recordid><startdate>2020</startdate><enddate>2020</enddate><creator>Ingner, Fredric J. L</creator><creator>Giustra, Zachary X</creator><creator>Novosedlik, Sebastian</creator><creator>Orthaber, Andreas</creator><creator>Gates, Paul J</creator><creator>Dyrager, Christine</creator><creator>Pilarski, Lukasz T</creator><general>Royal Society of Chemistry</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>7ST</scope><scope>7U6</scope><scope>8BQ</scope><scope>8FD</scope><scope>C1K</scope><scope>JG9</scope><scope>ACNBI</scope><scope>ADTPV</scope><scope>AOWAS</scope><scope>D8T</scope><scope>DF2</scope><scope>ZZAVC</scope><orcidid>https://orcid.org/0000-0001-8619-7745</orcidid><orcidid>https://orcid.org/0000-0001-5403-9902</orcidid><orcidid>https://orcid.org/0000-0002-9353-2238</orcidid><orcidid>https://orcid.org/0000-0001-5623-2837</orcidid><orcidid>https://orcid.org/0000-0003-4647-9769</orcidid></search><sort><creationdate>2020</creationdate><title>Mechanochemical synthesis of (hetero)aryl Au() complexes</title><author>Ingner, Fredric J. L ; Giustra, Zachary X ; Novosedlik, Sebastian ; Orthaber, Andreas ; Gates, Paul J ; Dyrager, Christine ; Pilarski, Lukasz T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c524t-7df7ea4fb29e32db2ab792223f494fc78fc3160cae90132f6e2e35d6579b7aae3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Aromatic compounds</topic><topic>Biocompatibility</topic><topic>Crystallography</topic><topic>Green chemistry</topic><topic>NMR</topic><topic>Nuclear magnetic resonance</topic><topic>Solvents</topic><topic>Substrates</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ingner, Fredric J. L</creatorcontrib><creatorcontrib>Giustra, Zachary X</creatorcontrib><creatorcontrib>Novosedlik, Sebastian</creatorcontrib><creatorcontrib>Orthaber, Andreas</creatorcontrib><creatorcontrib>Gates, Paul J</creatorcontrib><creatorcontrib>Dyrager, Christine</creatorcontrib><creatorcontrib>Pilarski, Lukasz T</creatorcontrib><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>Environment Abstracts</collection><collection>Sustainability Science Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Materials Research Database</collection><collection>SWEPUB Uppsala universitet full text</collection><collection>SwePub</collection><collection>SwePub Articles</collection><collection>SWEPUB Freely available online</collection><collection>SWEPUB Uppsala universitet</collection><collection>SwePub Articles full text</collection><jtitle>Green chemistry : an international journal and green chemistry resource : GC</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ingner, Fredric J. L</au><au>Giustra, Zachary X</au><au>Novosedlik, Sebastian</au><au>Orthaber, Andreas</au><au>Gates, Paul J</au><au>Dyrager, Christine</au><au>Pilarski, Lukasz T</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mechanochemical synthesis of (hetero)aryl Au() complexes</atitle><jtitle>Green chemistry : an international journal and green chemistry resource : GC</jtitle><date>2020</date><risdate>2020</risdate><volume>22</volume><issue>17</issue><spage>5648</spage><epage>5655</epage><pages>5648-5655</pages><issn>1463-9262</issn><issn>1463-9270</issn><eissn>1463-9270</eissn><abstract>Growing demand for sustainable chemical syntheses casts mechanochemistry in a new light as an environmentally benign alternative to traditional solvent-based methods. Given recent interest in Au(
i
) complexes for catalytic, materials, and medicinal applications, we developed a mechanochemical protocol to prepare (hetero)aryl Au(
i
) complexes under green conditions. The procedure reported here uses C-H or C-B activation to afford the corresponding Au(
i
) complexes in high yields. Our approach bypasses external heating, long reaction times and the use of toxic solvents. We demonstrate that mechanochemical C-H auration can be used on highly functionalised bioactive substrates. Mechanistic aspects of the C-H auration are discussed.
Shake, Rattle and Gold! Mechanochemistry enables the efficient and selective synthesis of organo-Au(
i
) complexes.</abstract><cop>Cambridge</cop><pub>Royal Society of Chemistry</pub><doi>10.1039/d0gc02263b</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0001-8619-7745</orcidid><orcidid>https://orcid.org/0000-0001-5403-9902</orcidid><orcidid>https://orcid.org/0000-0002-9353-2238</orcidid><orcidid>https://orcid.org/0000-0001-5623-2837</orcidid><orcidid>https://orcid.org/0000-0003-4647-9769</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1463-9262 |
| ispartof | Green chemistry : an international journal and green chemistry resource : GC, 2020, Vol.22 (17), p.5648-5655 |
| issn | 1463-9262 1463-9270 1463-9270 |
| language | eng |
| recordid | cdi_proquest_journals_2438576513 |
| source | Royal Society Of Chemistry Journals; SWEPUB Freely available online; Alma/SFX Local Collection |
| subjects | Aromatic compounds Biocompatibility Crystallography Green chemistry NMR Nuclear magnetic resonance Solvents Substrates |
| title | Mechanochemical synthesis of (hetero)aryl Au() complexes |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-20T20%3A55%3A49IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Mechanochemical%20synthesis%20of%20(hetero)aryl%20Au()%20complexes&rft.jtitle=Green%20chemistry%20:%20an%20international%20journal%20and%20green%20chemistry%20resource%20:%20GC&rft.au=Ingner,%20Fredric%20J.%20L&rft.date=2020&rft.volume=22&rft.issue=17&rft.spage=5648&rft.epage=5655&rft.pages=5648-5655&rft.issn=1463-9262&rft.eissn=1463-9270&rft_id=info:doi/10.1039/d0gc02263b&rft_dat=%3Cproquest_cross%3E2438576513%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2438576513&rft_id=info:pmid/&rfr_iscdi=true |