Design and evaluation of a biosynthesized cellulose drug releasing duraplasty

Decompressive craniectomy (DC) is a standard surgical procedure performed on stroke patients in which a portion of a skull is removed and a duraplasty membrane is applied onto the brain. While DC can significantly reduce the risk of death, it does not reverse the stroke damage. In this study, a nove...

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Veröffentlicht in:	Materials Science & Engineering C 2020-05, Vol.110, p.110677, Article 110677
Hauptverfasser:	Stumpf, Taisa Regina, Sandarage, Ryan Vimukthie, Galuta, Ahmad, Fournier, Patrick, Li, Tongda, Kirkwood, Kathlyn, Yi, Xinan, Tsai, Eve Chung, Cao, Xudong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biosynthesized cellulose Brain Cell Differentiation - drug effects Cells (biology) Cellulose Cellulose - biosynthesis Drug delivery Drug Delivery Systems Drug development Drug Liberation Dura mater Dura Mater - drug effects Dura Mater - surgery Epidermal Growth Factor - pharmacology Fabrication Fibroblast Growth Factor 2 - pharmacology Growth factors Head injuries Humans Inflammation Injuries Materials science Mechanical properties Membranes Modulus of elasticity Nerve regeneration Neurosurgery NSPC Physical properties Porosity Progenitor cells Prosthesis Implantation Rats, Sprague-Dawley Releasing Skull Spinal cord injuries Stroke Swelling ratio Traumatic brain injury Ultimate tensile strength
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