Effects of intrahippocampal injection of Leptin on seizure-induced cognitive impairment in male rats

Leptin is a peptide hormone secreted by adipose tissue. Leptin also acts on the hippocampus where it facilitates the induction of long-term potentiation. It also enhances NMDA receptor-mediated transmission. Previous studies have shown that Leptin plays a role in learning and memory. There is eviden...

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Veröffentlicht in:	Learning and motivation 2020-05, Vol.70, p.101612, Article 101612
Hauptverfasser:	Safa, Hanie, Sharifinejad, Asma, Ataollahi, Farshid, Haghparast, Elham, Esmaeilpour, Khadijeh
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose tissue Cognitive ability Cognitive Development Convulsions & seizures Glutamic acid receptors (ionotropic) Injection Intrahippocampal Learning Learning and memory Leptin Long-term potentiation Males Memory N-Methyl-D-aspartic acid receptors Pattern recognition PTZ Rodents Seizure Seizures Surgery
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