Piceatannol, a Natural Analog of Resveratrol, Exerts Anti-angiogenic Efficiencies by Blockage of Vascular Endothelial Growth Factor Binding to Its Receptor

Piceatannol is also named astrans-3,4,3 ',5 '-tetrahydroxy-stilbene, which is a natural analog of resveratrol and a polyphenol existing in red wine, grape and sugar cane. Piceatannol has been proved to possess activities of immunomodulatory, anti-inflammatory, antiproliferative and antican...

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Veröffentlicht in:	Molecules (Basel, Switzerland) Switzerland), 2020-08, Vol.25 (17), p.3769, Article 3769
Hauptverfasser:	Hu, Wei-Hui, Dai, Diana Kun, Zheng, Brody Zhong-Yu, Duan, Ran, Dong, Tina Ting-Xia, Qin, Qi-Wei, Tsim, Karl Wah-Keung
Format:	Artikel
Sprache:	eng
Schlagworte:	AKT protein Angiogenesis Angiogenesis Inhibitors - pharmacology Animals Antiangiogenics Binding Binding sites Biochemistry & Molecular Biology Biocompatibility Cancer therapies Cell adhesion & migration Cell growth Cell Proliferation Cell viability Chemical compounds Chemistry Chemistry, Multidisciplinary Colon Colon cancer Cytotoxicity Drug dosages Embryos Endothelial cells Growth factors herbal medicine Human Umbilical Vein Endothelial Cells - cytology Human Umbilical Vein Endothelial Cells - drug effects Human Umbilical Vein Endothelial Cells - metabolism Humans Immunomodulation Inflammation Investigations Life Sciences & Biomedicine Metabolism Mutation Neovascularization, Physiologic - drug effects Pharmacology Phosphorylation Physical Sciences Piceatannol Protein Binding Proteins pure compound Receptors, Vascular Endothelial Growth Factor - antagonists & inhibitors Receptors, Vascular Endothelial Growth Factor - metabolism Resveratrol Science & Technology Signal Transduction Stilbene Stilbenes - pharmacology Sugarcane Umbilical vein Vascular endothelial growth factor Vascular Endothelial Growth Factor A - antagonists & inhibitors Vascular Endothelial Growth Factor A - metabolism vasculogenesis VEGF VEGFR2 Wines Zebrafish
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