Bioactive and biostable hyaluronic acid-pullulan dermal hydrogels incorporated with biomimetic hydroxyapatite spheres

In this study, hyaluronic acid-pullulan injectable hydrogels were incorporated with biomimetic hydroxyapatite spheres and were modified using silane coupling agents in order to improve the physicochemical, mechanical, and biological performance of hydrogels. So the biomimetic hydroxyapatite spheres...

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Veröffentlicht in:	Materials Science & Engineering C 2020-07, Vol.112, p.110906, Article 110906
Hauptverfasser:	Ghorbani, Farnaz, Zamanian, Ali, Behnamghader, Aliasghar, Daliri Joupari, Morteza
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biocompatible Materials - chemistry Biocompatible Materials - metabolism Biocompatible Materials - pharmacology Biodegradation Biomedical materials Biomimetic hydroxyapatite Biomimetics Body fluids Cell adhesion Cell adhesion & migration Cell Adhesion - drug effects Cell Line Cell Survival - drug effects Cell viability Coupling agents Dermal filler Durability Durapatite - chemistry Field emission microscopy Gelatin Gels Glucans - chemistry Glycoside Hydrolases - metabolism Hyaluronic acid Hyaluronic Acid - chemistry Hydrogel Hydrogels Hydrogels - chemistry Hydrogels - metabolism Hydroxyapatite In vitro methods and tests Materials science Mice Microspheres Morphology Polymers Pullulan Rheology Scanning electron microscopy Siloxanes Spectrum analysis Storage modulus Structural analysis Submerging X-ray diffraction X-ray spectroscopy
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