Reply: Letter to the Editor: Exercise Interventions and Cardiovascular Health in Childhood Cancer: A Meta-Analysis
Dear Editor We sincerely appreciate the nice comments by Drs. P.V. da Costa Ghignatti and R. Pereira de Lima 1 concerning our recent meta-analysis assessing the effects of physical exercise interventions on cardiovascular endpoints in childhood cancer survivors 2. They are quite right to remain that...
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| Veröffentlicht in: | International journal of sports medicine 2020-08, Vol.41 (9), p.629-629 |
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| creator | Morales, Javier S. Valenzuela, Pedro L. Herrera-Olivares, Alba M. Baño-Rodrigo, Antonio Castillo-García, Adrián Rincón-Castanedo, Cecilia Martín-Ruiz, Asunción San Juan, Alejandro F. Fiuza-Luces, Carmen Lucia, Alejandro |
| description | Dear Editor
We sincerely appreciate the nice comments by Drs. P.V. da Costa Ghignatti and R.
Pereira de Lima 1 concerning our recent
meta-analysis assessing the effects of physical exercise interventions on
cardiovascular endpoints in childhood cancer survivors 2. They are quite right to remain that even
non-significant improvements in cardiorespiratory fitness (CRF) might be
clinically relevant. Indeed, we still do not know if CRF increments of a
theoretically low magnitude (
i. e.
, |
| doi_str_mv | 10.1055/a-1195-7025 |
| format | Article |
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We sincerely appreciate the nice comments by Drs. P.V. da Costa Ghignatti and R.
Pereira de Lima 1 concerning our recent
meta-analysis assessing the effects of physical exercise interventions on
cardiovascular endpoints in childhood cancer survivors 2. They are quite right to remain that even
non-significant improvements in cardiorespiratory fitness (CRF) might be
clinically relevant. Indeed, we still do not know if CRF increments of a
theoretically low magnitude (
i. e.
, <1 metabolic
equivalent) might have a prognostic value in the context of pediatric cancer and
treatment-associated cardiotoxicity. We also agree that unsupervised exercise
interventions are unlikely to be as effective as tailored programs, especially
because the latter allow for intensity to being adequately controlled and thus
gradually increased. It is indeed our opinion, after long years of experience
working with children with cancer as well as with other debilitated clinical
populations, that there is always room for physiological improvement and ideally
loads should be gradually improved instead of remaining stable.</description><identifier>ISSN: 0172-4622</identifier><identifier>EISSN: 1439-3964</identifier><identifier>DOI: 10.1055/a-1195-7025</identifier><language>eng</language><publisher>Stuttgart · New York: Georg Thieme Verlag KG</publisher><subject>Letter to the Editor ; Meta-analysis</subject><ispartof>International journal of sports medicine, 2020-08, Vol.41 (9), p.629-629</ispartof><rights>Copyright Georg Thieme Verlag Stuttgart Aug 2020</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c287t-a58746028d41826cf08cb9c98f7a5d357a81e06d792799d569ae4867897919fe3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.thieme-connect.de/products/ejournals/pdf/10.1055/a-1195-7025.pdf$$EPDF$$P50$$Gthieme$$H</linktopdf><linktohtml>$$Uhttps://www.thieme-connect.de/products/ejournals/html/10.1055/a-1195-7025$$EHTML$$P50$$Gthieme$$H</linktohtml><link.rule.ids>314,780,784,3017,3018,27924,27925,54559,54560</link.rule.ids></links><search><creatorcontrib>Morales, Javier S.</creatorcontrib><creatorcontrib>Valenzuela, Pedro L.</creatorcontrib><creatorcontrib>Herrera-Olivares, Alba M.</creatorcontrib><creatorcontrib>Baño-Rodrigo, Antonio</creatorcontrib><creatorcontrib>Castillo-García, Adrián</creatorcontrib><creatorcontrib>Rincón-Castanedo, Cecilia</creatorcontrib><creatorcontrib>Martín-Ruiz, Asunción</creatorcontrib><creatorcontrib>San Juan, Alejandro F.</creatorcontrib><creatorcontrib>Fiuza-Luces, Carmen</creatorcontrib><creatorcontrib>Lucia, Alejandro</creatorcontrib><title>Reply: Letter to the Editor: Exercise Interventions and Cardiovascular Health in Childhood Cancer: A Meta-Analysis</title><title>International journal of sports medicine</title><addtitle>Int J Sports Med</addtitle><description>Dear Editor
We sincerely appreciate the nice comments by Drs. P.V. da Costa Ghignatti and R.
Pereira de Lima 1 concerning our recent
meta-analysis assessing the effects of physical exercise interventions on
cardiovascular endpoints in childhood cancer survivors 2. They are quite right to remain that even
non-significant improvements in cardiorespiratory fitness (CRF) might be
clinically relevant. Indeed, we still do not know if CRF increments of a
theoretically low magnitude (
i. e.
, <1 metabolic
equivalent) might have a prognostic value in the context of pediatric cancer and
treatment-associated cardiotoxicity. We also agree that unsupervised exercise
interventions are unlikely to be as effective as tailored programs, especially
because the latter allow for intensity to being adequately controlled and thus
gradually increased. It is indeed our opinion, after long years of experience
working with children with cancer as well as with other debilitated clinical
populations, that there is always room for physiological improvement and ideally
loads should be gradually improved instead of remaining stable.</description><subject>Letter to the Editor</subject><subject>Meta-analysis</subject><issn>0172-4622</issn><issn>1439-3964</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNptkE9LwzAYh4MoOP-c_AIBb0o1SZMm2W2U6QYTQfRcYvqWZnTNTLLhvr0tE7x4eg_vw8OPB6EbSh4oEeLRZJRqkUnCxAmaUJ7rLNcFP0UTQiXLeMHYObqIcU0I5ZrmExTeYNsdpngFKUHAyePUAp7XLvkwxfNvCNZFwMt--O6hT873EZu-xqUJtfN7E-2uMwEvwHSpxa7HZeu6uvV-RHoLg2WGXyCZbNab7hBdvEJnjekiXP_eS_TxNH8vF9nq9XlZzlaZZUqmzAgleUGYqjlVrLANUfZTW60aaUSdC2kUBVLUUjOpdS0KbYCrQiotNdUN5Jfo9ujdBv-1g5iqtd-FYUSsGM8511pQNlD3R8oGH2OAptoGtzHhUFFSjVErU41RqzHqQN8d6dQ62MCf8T_4B_ewdd0</recordid><startdate>202008</startdate><enddate>202008</enddate><creator>Morales, Javier S.</creator><creator>Valenzuela, Pedro L.</creator><creator>Herrera-Olivares, Alba M.</creator><creator>Baño-Rodrigo, Antonio</creator><creator>Castillo-García, Adrián</creator><creator>Rincón-Castanedo, Cecilia</creator><creator>Martín-Ruiz, Asunción</creator><creator>San Juan, Alejandro F.</creator><creator>Fiuza-Luces, Carmen</creator><creator>Lucia, Alejandro</creator><general>Georg Thieme Verlag KG</general><general>Georg Thieme Verlag Stuttgart</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>K9.</scope><scope>NAPCQ</scope></search><sort><creationdate>202008</creationdate><title>Reply: Letter to the Editor: Exercise Interventions and Cardiovascular Health in Childhood Cancer: A Meta-Analysis</title><author>Morales, Javier S. ; Valenzuela, Pedro L. ; Herrera-Olivares, Alba M. ; Baño-Rodrigo, Antonio ; Castillo-García, Adrián ; Rincón-Castanedo, Cecilia ; Martín-Ruiz, Asunción ; San Juan, Alejandro F. ; Fiuza-Luces, Carmen ; Lucia, Alejandro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c287t-a58746028d41826cf08cb9c98f7a5d357a81e06d792799d569ae4867897919fe3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Letter to the Editor</topic><topic>Meta-analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Morales, Javier S.</creatorcontrib><creatorcontrib>Valenzuela, Pedro L.</creatorcontrib><creatorcontrib>Herrera-Olivares, Alba M.</creatorcontrib><creatorcontrib>Baño-Rodrigo, Antonio</creatorcontrib><creatorcontrib>Castillo-García, Adrián</creatorcontrib><creatorcontrib>Rincón-Castanedo, Cecilia</creatorcontrib><creatorcontrib>Martín-Ruiz, Asunción</creatorcontrib><creatorcontrib>San Juan, Alejandro F.</creatorcontrib><creatorcontrib>Fiuza-Luces, Carmen</creatorcontrib><creatorcontrib>Lucia, Alejandro</creatorcontrib><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><jtitle>International journal of sports medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Morales, Javier S.</au><au>Valenzuela, Pedro L.</au><au>Herrera-Olivares, Alba M.</au><au>Baño-Rodrigo, Antonio</au><au>Castillo-García, Adrián</au><au>Rincón-Castanedo, Cecilia</au><au>Martín-Ruiz, Asunción</au><au>San Juan, Alejandro F.</au><au>Fiuza-Luces, Carmen</au><au>Lucia, Alejandro</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Reply: Letter to the Editor: Exercise Interventions and Cardiovascular Health in Childhood Cancer: A Meta-Analysis</atitle><jtitle>International journal of sports medicine</jtitle><addtitle>Int J Sports Med</addtitle><date>2020-08</date><risdate>2020</risdate><volume>41</volume><issue>9</issue><spage>629</spage><epage>629</epage><pages>629-629</pages><issn>0172-4622</issn><eissn>1439-3964</eissn><abstract>Dear Editor
We sincerely appreciate the nice comments by Drs. P.V. da Costa Ghignatti and R.
Pereira de Lima 1 concerning our recent
meta-analysis assessing the effects of physical exercise interventions on
cardiovascular endpoints in childhood cancer survivors 2. They are quite right to remain that even
non-significant improvements in cardiorespiratory fitness (CRF) might be
clinically relevant. Indeed, we still do not know if CRF increments of a
theoretically low magnitude (
i. e.
, <1 metabolic
equivalent) might have a prognostic value in the context of pediatric cancer and
treatment-associated cardiotoxicity. We also agree that unsupervised exercise
interventions are unlikely to be as effective as tailored programs, especially
because the latter allow for intensity to being adequately controlled and thus
gradually increased. It is indeed our opinion, after long years of experience
working with children with cancer as well as with other debilitated clinical
populations, that there is always room for physiological improvement and ideally
loads should be gradually improved instead of remaining stable.</abstract><cop>Stuttgart · New York</cop><pub>Georg Thieme Verlag KG</pub><doi>10.1055/a-1195-7025</doi><tpages>1</tpages></addata></record> |
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| subjects | Letter to the Editor Meta-analysis |
| title | Reply: Letter to the Editor: Exercise Interventions and Cardiovascular Health in Childhood Cancer: A Meta-Analysis |
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