Drinking to death: Hyponatraemia induced by synthetic phenethylamines

[Display omitted] •Hyponatraemia is a potential pathophysiological consequence of phenethylamine abuse.•Phenethylamine-induced hyponatraemia is related to high levels of circulating antidiuretic hormone (ADH).•ADH secretion via serotonergic activation results in inappropriate water retention.•The ma...

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Veröffentlicht in:	Drug and alcohol dependence 2020-07, Vol.212, p.108045, Article 108045
Hauptverfasser:	Faria, Ana Carolina, Carmo, Helena, Carvalho, Félix, Silva, João Pedro, Bastos, Maria de Lourdes, Dias da Silva, Diana
Format:	Artikel
Sprache:	eng
Schlagworte:	3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) Alcohol Drinking - adverse effects Alcohol Drinking - metabolism Alkaloids - adverse effects Amphetamine Amphetamine - adverse effects Amphetamines Antidiuretic hormone (ADH) or arginine vasopressin (AVP) Antidiuretics Cerebellum Coma Drinking - physiology Drinking water Drug abuse Ecstasy Ecstasy drug Edema Fever Fluid intake Humans Hyperthermia Hyponatremia Hyponatremia - chemically induced Hyponatremia - diagnosis Hyponatremia - metabolism Illicit Drugs - adverse effects Intoxication Life threatening MDMA Metabolic activation Metabolic rate Methamphetamine N-Methyl-3,4-methylenedioxyamphetamine - adverse effects Neurophysins - adverse effects Neurophysins - metabolism Oedema Phenethylamine Phenethylamines - adverse effects Polydipsia Prevention programs Protein Precursors - adverse effects Protein Precursors - metabolism Reabsorption Serotonin Serotonin syndrome Side effects Sodium State-of-the-art reviews Synthetic cathinone Tonsil Toxicity Vasopressins - adverse effects Vasopressins - metabolism Women
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